Publications by authors named "F C Q Mello"

Per- and polyfluoroalkyl substances (PFAS) exhibit widespread global distribution, extending to remote regions including Antarctica. Despite potential adverse effects on seabirds, PFAS exposure among Antarctic penguins remains poorly studied. We investigated the occurrence of 29 PFAS compounds in feathers and excreta of Gentoo penguins (Pygoscelis papua) from Fildes Bay, Antarctica.

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Background: Intrahepatic cholangiocarcinoma (iCCA) was considered a contraindication for liver transplantation. However, recent studies have shown that highly selected cases of patients with a good response to neoadjuvant therapy may achieve acceptable survival rates when following liver transplantation.

Aims: To present two cases of patients with iCCA, without extrahepatic disease, who underwent living donor liver transplantation after receiving neoadjuvant chemotherapy.

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Article Synopsis
  • Existing vaccines for hepatitis B are effective, but the virus remains a significant health issue due to challenges like cccDNA and potential reinfection.
  • RNA interference (RNAi) is being explored as a promising treatment strategy for chronic hepatitis B, offering a new approach to silence the virus.
  • A review analyzed 76,949 studies, narrowing it down to 226 key reports, highlighting RNAi's potential while calling for more research to bridge the gap between laboratory findings and real-world treatment applications.
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Article Synopsis
  • The Brazilian Amazon is a key area for hepatitis Delta virus (HDV) with hard-to-reach locations, making it crucial to study how the virus spreads there.
  • A molecular analysis of HDV cases, involving 35 patients from Rondônia, Brazil, was conducted using PCR and sequencing to track the virus's evolution and transmission over time.
  • Findings indicate that all samples were HDV-3, with an estimated entry into Brazil around 1820, suggesting complex migration patterns throughout the region over the past two centuries.*
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In 2022-2023, the first survey of clinicians regarding infection of rabbits was undertaken. The purpose was to assess the current worldwide knowledge of clinicians regarding influence of breed and age, clinical presentations, use of various diagnostic tools, and treatment regimens and to explore how responses may differ by geographic location. Identifying mostly as exotic animal clinicians, 339 respondents participated, with nearly half from the United States and the remainder from 35 other countries.

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