Publications by authors named "F C Kaiser"
Article Synopsis
- - The study explores the implementation of antibiotic stewardship (ABS) measures in Specialized Outpatient Palliative Care (SAPV) in Germany, emphasizing the need for optimizing antibiotic use among palliative patients, predominantly those with malignant diseases.
- - Through interviews with 15 experts, the research highlights that ABS can enhance safety in antibiotic prescribing and improve patients' quality of life, although its implementation is challenging and may require additional training and support for SAPV staff.
- - The findings suggest that while implementing ABS in SAPV is feasible, it necessitates collaboration with existing ABS teams to ensure better care for palliative patients and support for healthcare providers.
The randomized FIRE-4.5 (AIO KRK0116) trial compared first-line therapy with FOLFOXIRI (folinic acid, fluorouracil, oxaliplatin, and irinotecan) plus either cetuximab or bevacizumab in B-Raf proto-oncogene, serine/threonine kinase (BRAF) V600E-mutant metastatic colorectal cancer (mCRC) patients. This study was accompanied by a prospective translational project analyzing cell-free circulating tumor DNA (ctDNA) in plasma to test whether ctDNA analysis may help to guide clinical treatment decision making.
View Article and Find Full Text PDFAttitude toward nature and environmental attitude are two distinct propensities that both further learning about the environment. The present study builds upon prior research by investigating the role of attitude toward nature in learning about environmental issues. In a sample of 1,486 university, middle and high school students ( = 15.
View Article and Find Full Text PDFAnalysis of liver tissue from a Cape penguin that died with hepatitis at a zoo in Germany revealed Umatilla virus. Testing uncovered Umatilla virus RNA in samples from 2 other deceased Cape penguins at the zoo. Our results expand knowledge of the prevalence of this virus in bird species across Germany.
View Article and Find Full Text PDFArticle Synopsis
- - Cornelia de Lange syndrome (CdLS) is a rare genetic disorder that impacts physical development and cognitive abilities, primarily caused by mutations in genes linked to the cohesin complex, though many cases remain undiagnosed.
- - The study presents a family case where multiple members have an intragenic duplication in the AFF2 gene, identified using advanced genomic technologies like high-resolution array Comparative Genomic Hybridization and next-generation sequencing.
- - The research shows a clear correlation between the AFF2 gene mutation and the CdLS phenotype, with the affected individuals displaying significant changes in gene expression and X-inactivation patterns compared to an unaffected relative, suggesting that AFF2 should be included in molecular diagnosis for CdLS.