Publications by authors named "F C Hasenauer"
Article Synopsis
- The study examines how spontaneous replication errors occur in the E. coli genome despite mechanisms meant to prevent them.
- Researchers identified specific hotspots for these errors, linked to factors such as DNA stability, sequence types that cause slippage, and structures that can stall DNA replication.
- Findings suggest that hotspots are associated with certain proteins, gene expression levels, and single-stranded DNA, highlighting complex interactions that affect the accuracy of genetic information transmission.
Caprine brucellosis is an infectious, contagious zoonotic disease caused by Brucella melitensis. Multiple factors, including host genetics, can influence the outcome of the exposure to Brucella; and it is expected that genetic variants that affect the host innate immune response could have a key role in Brucella infection and pathogenesis. In this study, we evaluated if polymorphisms in innate immunity-related genes are associated with results of Brucella infection in goats.
View Article and Find Full Text PDFBrucellosis is an important zoonotic disease caused by infection with Brucella spp. It generates major economic losses in livestock production worldwide. Goats are the principal hosts of B.
View Article and Find Full Text PDFBrucellosis is the leading zoonosis on a worldwide scale and constitutes a major public health threat in many regions of the world. Several molecular markers associated with natural resistance to intracellular bacterial infection have been identified. Recently seven single-nucleotide polymorphisms (SNPs) located in the PTPRT gene were associated with resistance to Mycobacterium bovis infection in cattle.
View Article and Find Full Text PDFGoats are susceptible to brucellosis and the detection of Brucella-infected animals is carried out by serological tests. In other ruminant species, polymorphisms in microsatellites (Ms) of 3' untranslated region (3'UTR) of the solute carrier family 11 member A1 (SLC11A1) gene were associated with resistance to Brucella abortus infection. Goats present two polymorphic Ms at the 3'UTR end of SLC11A1 gene, called regions A and B.
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