Resting-state fMRI activation is associated with parent-reported phenotypic features of autism in early adolescence.

Introduction: Autism Spectrum Disorder (ASD) is characterized by deficits in social cognition, self-referential processing, and restricted repetitive behaviors. Despite the established clinical symptoms and neurofunctional alterations in ASD, definitive biomarkers for ASD features during neurodevelopment remain unknown. In this study, we aimed to explore if activation in brain regions of the default mode network (DMN), specifically the medial prefrontal cortex (MPC), posterior cingulate cortex (PCC), superior temporal sulcus (STS), inferior frontal gyrus (IFG), angular gyrus (AG), and the temporoparietal junction (TPJ), during resting-state functional magnetic resonance imaging (rs-fMRI) is associated with possible phenotypic features of autism (PPFA) in a large, diverse youth cohort.

Prevalence and Patterns of Social Media Use in Early Adolescents.

Objective: To describe patterns of social media use, including underage (under 13 years) use and sex differences, in a diverse, national sample of early adolescents in the U.S.

Methods: We analyzed the social media use data in the Adolescent Brain Cognitive Development Study (2019-2021, Year 3), which includes a national sample of early adolescents in the U.

Resilience Training Web App for National Health Service Keyworkers: Pilot Usability Study.

Background: It is well established that frontline health care staff are particularly at risk of stress. Resilience is important to help staff to manage daily challenges and to protect against burnout.

Objective: This study aimed to assess the usability and user perceptions of a resilience training web app developed to support health care keyworkers in understanding their own stress response and to help them put into place strategies to manage stress and to build resilience.

Cyberbullying Victimization Among Transgender and Gender-Questioning Early Adolescents.

Objective: To determine the association between transgender or gender-questioning identity and cyberbullying victimization in a diverse national sample of early adolescents in the United States.

Methods: We analyzed cross-sectional data from the Adolescent Brain Cognitive Development Study (year 3, 2019-2021, 11-14 years old, 48.8% female, 47.

Gender diversity and daily steps: Findings from the Adolescent Brain Cognitive Development Study.

Purpose: To examine the association between multiple dimensions of gender diversity and physical activity (daily steps) in a diverse national sample of early adolescents in the United States.

Methods: This study analyzed Year 2 data from the Adolescent Brain Cognitive Development (ABCD) Study (N = 6038, M=12.0 years).