Publications by authors named "F Buonaguro"
Article Synopsis
- * These micropeptides can either suppress or promote tumors, making them potential biomarkers for early cancer diagnosis and targets for therapy.
- * The review explores the roles of micropeptides from long non-coding RNAs, microRNAs, and circular RNAs in various cancers, while also addressing current challenges and future research directions in this area of cancer biology.
Background: We have recently shown extensive sequence and conformational homology between tumor-associated antigens (TAAs) and antigens derived from microorganisms (MoAs). The present study aimed to assess the breadth of T-cell recognition specific to MoAs and the corresponding TAAs in healthy subjects (HS) and patients with cancer (CP).
Method: A library of > 100 peptide-MHC (pMHC) combinations was used to generate DNA-barcode labelled multimers.
Chronic Viral Infections and Cancer, Openings for Therapies and Vaccines.
Cancers (Basel)
February 2024
Infections are responsible for approximately one out of six cases of cancer worldwide [...
View Article and Find Full Text PDFBackground: Early diagnosis of hepatocellular carcinoma (HCC) is essential towards the improvement of prognosis and patient survival. Circulating markers such as α-fetoprotein (AFP) and micro-RNAs represent useful tools but still have limitations. Identifying new markers can be fundamental to improve both diagnosis and prognosis.
View Article and Find Full Text PDF