Publications by authors named "F Brunelle"
Background And Purpose: The characteristics of large vessel occlusion (LVO) in the acute phase of pediatric arterial ischemic stroke and their natural history according to stroke etiology are poorly explored. This studied aimed at describing the prevalence and the radiological evolution of LVO in pediatric AIS.
Materials And Methods: This single-center retrospective study included consecutive non-neonate children with acute arterial ischemic stroke, intracranial proximal LVO in the anterior circulation (MCA, anterior cerebral artery, and/or ICA), and clinical and imaging follow-up for at least 18 months, during a 9-year period.
Article Synopsis
- A study investigated the safety and effectiveness of only 6 months of dual-antiplatelet treatment (DAPT) following the implantation of a BioMatrix biodegradable-polymer coated biolimus-eluting stent (BP-BES) after percutaneous coronary intervention (PCI).
- The research included 2,038 patients in France, who were monitored for 6 and 24 months, focusing on major adverse cardiac and cerebrovascular events (MACCE) as the primary outcome.
- Results showed low rates of MACCE, stent thrombosis, and major bleeding at both 6 and 24 months, suggesting that a shorter DAPT duration is both safe and effective for patients with the BP-BES stent.
Background: Recurrence following obliteration of brain arteriovenous malformations (AVMs) is common in children surgically treated, but recurrences following endovascular (EVT) and radiosurgical approaches are scantily reported.
Objective: To analyze the rates and risk factors for AVM recurrence after obliteration in a single-center cohort of children with ruptured AVMs treated with multimodal approaches, and to carry out a comprehensive review and meta-analysis of current data.
Methods: Children with ruptured AVMs between 2000 and 2019 enrolled in a prospective registry were retrospectively screened and included after angiographically determined obliteration to differentiate children with/without recurrence.
Article Synopsis
- Pediatric nontraumatic intracerebral hemorrhage is common in children and often caused by arteriovenous shunts (AVS), making early diagnosis crucial for preventing future hemorrhages.
- A study examined the effectiveness of arterial spin labeling (ASL) MRI in detecting AVS in children who experienced hemorrhage between 2011 and 2019, finding that ASL performed better than other imaging methods like CT angiography.
- ASL demonstrated high sensitivity (90.2%) and specificity (97.2%) for identifying AVS, making it a valuable tool in acute evaluations of pediatric stroke.
Objective: Rupture of brain arteriovenous malformation (AVM) is the main etiology of intracerebral hemorrhage (ICH) in children. Ensuing intracranial hypertension is among the modifiable prognosis factors and sometimes requires emergency hemorrhage evacuation (HE). The authors aimed to analyze variables associated with HE in children with ruptured AVM.
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