Publications by authors named "F Boulogne"
Article Synopsis
- Genetic variants found in GWAS are mostly non-coding and have subtle effects on genes, while Mendelian disease variants are coding and directly influence diseases.
- The study connects common and rare genetic diseases by analyzing how common variants affect gene co-expression across various tissues, using a tool called Downstreamer on 88 GWAS traits.
- Key findings show that important downstream genes related to common traits, like height, are often linked to Mendelian disease genes, with many being located outside GWAS loci, indicating complex regulatory interactions.
We present an experimental study on the evaporation of drops on fibers. More specifically, we focus on the droplet lifetime both in quiescent air and in an air flow of constant velocity. We propose a model to describe the evaporation rate and lifetime in a purely diffusive regime, which includes the liquid cooling associated with evaporation and the thermal conductivity of the atmosphere and the fiber.
View Article and Find Full Text PDFArticle Synopsis
- The study explores the complex genetic background of cancer, focusing on the connection between somatic mutations and germline risk factors from genome-wide association studies (GWAS).
- Researchers analyzed co-expression patterns of genes identified in GWAS for various cancers, finding that many of these genes are significant in their relationship with known cancer driver genes.
- The findings suggest that tissue-specific co-expression networks can explain how different sets of genes—those with germline risk factors and those with somatic mutations—can lead to the same type of cancer, thus bridging the gap between these two genetic influences.
We consider the lifetime of rectangular vertical soap films and we explore the influence of relative humidity and both dimensions on the stability of large soap films, reaching heights of up to 1.2 m. Using an automated rupture detection system, we achieve a robust statistical measurement of their lifetimes and we also measure the film thinning dynamics.
View Article and Find Full Text PDFMany ionic surfactants, such as sodium dodecyl sulfate (SDS) crystallize out of solution if the temperature falls below the crystallization boundary. The crystallization temperature is impacted by solution properties and can be decreased with the addition of salt. We studied SDS crystallization at liquid/vapor interfaces from solutions at high ionic strength (sodium chloride).
View Article and Find Full Text PDF