Publications by authors named "F Bouchart"
For decades, calcium phosphate (CaP)-based ceramics have been used for coating of bone and joint substitutes after arthroplasty due to their biocompatible properties. Infections following orthopedic replacement occur in 1%-5% of cases, causing serious complications. Biofilm formation either on the biomaterial's surface or on patient's tissues greatly enhances the resistance against antibiotic treatments and can induce a chronic infection, emphasizing the need for novel antimicrobial delivery systems.
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- Gene duplication, particularly of the porin OmpF, plays a significant role in the evolution of microbial genomes, impacting their interaction with host plants, especially in the case of soft rot disease.
- The OmpF gene duplication was found to be detrimental to the virulence of the pathogen, thus contradicting the typical idea that duplicated genes always confer an advantage.
- The regulation of the EnvZ-OmpR system, which responds to pH changes, is complicated by plant defenses that produce phenolic acids, ultimately suppressing the expression of potentially harmful genes during infection.
Background: Venoarterial extra corporeal life support (ECLS) is the treatment of choice of Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) class 1 patients, but left ventricle (LV) overload is a complication of ECLS. Unloading the LV by adding Impella 5.0 to ECLS in Impella used in combination with venoarterial extracorporeal membrane oxygenation (ECMELLA) configuration is recommended only in patients with acceptable prognosis.
View Article and Find Full Text PDFTricalcium phosphate (TCP) is a prosthetic material commonly used as a bone substitute to repair osteoarticular diseases and injuries. In this type of bone reconstruction surgery, antibiotics remain the common preventive and therapeutic treatment for bacterial infection. Nevertheless, the emergence of multi-resistant strains requires complimentary or alternative treatments.
View Article and Find Full Text PDFBackground: Surgical site complications represent major concerns in many surgical specialties and lead to an increased length of hospital stay and the need for additional treatments and care. This investigation aimed to report survey data from the introduction of the PICO negative pressure wound therapy system (Smith & Nephew, Hull, United Kingdom) in a single hospital in France regarding cardiac surgical procedures through standard median sternotomy.
Methods: The patients in this study were at high risk of developing surgical site infections.