Publications by authors named "F Beuret Blanquart"

The pangenome of a species is the set of all genes carried by at least one member of the species. In bacteria, pangenomes can be much larger than the set of genes carried by a single organism. Many questions remain unanswered regarding the evolutionary forces shaping the patterns of presence/absence of genes in pangenomes of a given species.

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Escherichia coli is an increasingly antibiotic-resistant opportunistic pathogen. Few data are available on its ecological and evolutionary dynamics in its primary commensal niche, the vertebrate gut. Using Illumina and/or Nanopore technologies, we sequenced whole genomes of 210 E.

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Article Synopsis
  • The study focuses on improving the quantitative validation of theoretical models in infectious disease dynamics, particularly for a polymorphic viral population.
  • It details an experiment involving a temperate bacteriophage to assess how epidemiological dynamics affect virus transmission and virulence.
  • The findings highlight the importance of directly modeling infected bacterial cells to enhance fit with experimental data, and introduce estimations for key traits of the viral strains, ultimately enriching our understanding of the phage's evolutionary epidemiology.
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People with HIV may report neurocognitive complaints, with or without associated neurocognitive impairment, varying between individuals and populations. While the HIV genome could play a major role, large systematic viral genome-wide screens to date are lacking. The Swiss HIV Cohort Study biannually enquires neurocognitive complaints.

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Article Synopsis
  • SARS-CoV-2 variants of concern (VOCs), like Alpha from the UK, spread silently before being officially recognized, complicating timely interventions.
  • Researchers analyzed the early spread of Alpha using various data sources, revealing that silent circulation could last from days to months and was influenced by the amount of genomic sequencing.
  • The study highlights that implementing social restrictions in certain regions might have helped slow down local transmission, emphasizing the importance of proactive measures during emerging threats.
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