Publications by authors named "F Bernardini"
Genetic control - the deliberate introduction of genetic traits to control a pest or vector population - offers a powerful tool to augment conventional mosquito control tools that have been successful in reducing malaria burden but that are compromised by a range of operational challenges. Self-sustaining genetic control strategies have shown great potential in laboratory settings, but hesitancy due to their invasive and persistent nature may delay their implementation. Here, instead, we describe a self-limiting strategy, designed to have geographically and temporally restricted effect, based on a Y chromosome-linked genome editor (YLE).
View Article and Find Full Text PDFBackground: Complete bicorporeal uterus, double cervix and obstructive longitudinal vaginal septum (classified as U3bC2V2 according to ESHRE/ESGE classification) is a rare congenital anomaly of the genital tract. This condition is typically associated with ipsilateral renal agenesis and is known as Herlyn-Werner-Wunderlich syndrome or OHVIRA (Obstructed HemiVagina and Ipsilateral Renal Anomaly) syndrome. The primary symptoms include dysmenorrhea and pelvic pain, which usually manifest after menarche due to haematocolpos in the obstructed hemivagina.
View Article and Find Full Text PDFSuperconductivity in infinite layer nickelates Nd_{1-x}Sr_{x}NiO_{2} has so far been achieved only in thin films, raising questions on the role of substrates and interfaces. Given the challenges associated with their synthesis it is imperative to identify their intrinsic properties. We use resonant inelastic x-ray scattering to investigate the influence of the SrTiO_{3} capping layer on the excitations of Nd_{1-x}Sr_{x}NiO_{2} (x=0 and 0.
View Article and Find Full Text PDFArticle Synopsis
- Isolation mechanisms in the Anopheles gambiae complex, important malaria vectors, include both pre-zygotic barriers reducing gene flow and post-zygotic issues like sterility in hybrid males and decreased fertility in hybrid females.
- Genetic studies have revealed that hybrid incompatibility is largely influenced by interactions on the X chromosome, while also noting differences in the fertility of hybrid males based on the direction of the cross.
- A study exploring the roles of mitochondrial DNA in hybrid incompatibilities found that switching mitochondrial DNA between species did not improve hybrid male fertility, suggesting it may not significantly contribute to these incompatibilities.
Article Synopsis
- - This study investigates how effective MRI is at identifying remaining cervical cancer after patients receive platinum-based neoadjuvant chemotherapy, particularly in pregnant women.
- - The research involved 12 pregnant patients treated between 2010 and 2021, assessing tumor size and status through MRI before and after treatment, where most patients showed residual disease post-therapy.
- - Results indicate that MRI is highly sensitive (100%) in detecting residual disease, suggesting it is a reliable method to evaluate treatment response in pregnant cervical cancer patients.