Publications by authors named "F Benninger"
Primary (AL) systemic amyloidosis is an uncommon disorder in which immunoglobulin light chains are deposited in the tissues as amyloid, resulting in organ dysfunction. The initial symptoms are frequent fatigue and weight loss, and common manifestations include nephrotic syndrome, cardiomyopathy, peripheral neuropathy or hepatomegaly. Histological examination reveals some degree of amyloid deposition in virtually every organ system except the central nervous system (CNS).
View Article and Find Full Text PDFObjective: Blood-brain barrier dysfunction (BBBD) has been linked to various neurological disorders, including epilepsy. This study aims to utilize dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to identify and compare brain regions with BBBD in patients with epilepsy (PWE) and healthy individuals.
Methods: We scanned 50 drug-resistant epilepsy (DRE) patients and 58 control participants from four global specialized epilepsy centers using DCE-MRI.
Epilepsy is a severe chronic neurological disease affecting 60 million people worldwide. Primary treatment is with anti-seizure medicines (ASMs), but many patients continue to experience seizures. We used retrospective insurance claims data on 280,587 patients with uncontrolled epilepsy (UE), defined as status epilepticus, need for a rescue medicine, or admission or emergency visit for an epilepsy code.
View Article and Find Full Text PDFArticle Synopsis
- Quantum mechanics emerges from a framework called Dendrographic Hologram Theory (DHT), which conceptualizes the universe as a tree of events represented by a dendrogram, reflecting hierarchical relationships among them.
- By using a generalized quantization scheme, inspired by Smolin, the authors focus on quantizing the differences between events rather than the events themselves, ultimately deriving Bohmian mechanics, which can effectively describe quantum experiments despite being a non-mainstream approach.
- The paper also discusses the compatibility of DHT with general relativity, noting that while DHT exhibits nonlocal properties, this nonlocality pertains to relational interactions among events rather than conventional spatial nonlocality, thus making Bohmian mechanics more approachable.