Publications by authors named "F Bellissimo-Rodrigues"

Background: Tuberculosis (TB) remains a significant public health concern, particularly in low-to-middle-income countries. Healthcare workers (HCWs) are at a higher risk due to prolonged exposure. The World Health Organization (WHO) has proposed guidelines focusing on administrative interventions, structural interventions, and personal protective equipment (PPE) usage to mitigate this risk.

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Purpose: Tolerance and persistence occur "silently" in bacteria categorized as susceptible by antimicrobial susceptibility testing in clinical microbiology laboratories. They are different from resistance phenomena, not well-studied, and often remain unnoticeable. We aimed to investigate and characterize ceftazidime-avibactam (CZA) tolerance/persistence in 80 Klebsiella pneumoniae isolates from bloodstream infections.

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Article Synopsis
  • - This study explored neurological effects of COVID-19 by analyzing cerebral glycolytic metabolism in patients with mild long COVID cognitive symptoms and comparing them to healthy volunteers using PET/CT scans.
  • - Despite not finding significant differences in glucose metabolism between the two groups, researchers noted hypometabolism in 15 brain regions and hypermetabolism in 11 regions in the mild COVID group, particularly in areas related to cognitive function and emotional regulation.
  • - The authors suggest that future research should involve larger samples and consider correlating these metabolic changes with cognitive and psychiatric assessments to better understand the potential neurological impacts of COVID-19.
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  • The study aimed to investigate the ophthalmological effects of dry eye disease on the quality of life of COVID-19 survivors who had been hospitalized.
  • The evaluation included various tests for dry eye disease and a quality of life questionnaire, with most patients reporting severe or critical COVID-19 symptoms.
  • Results showed a significant link between dry eye symptoms and lower quality of life ratings, indicating that those suffering from dry eye experienced worse overall health and well-being.
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Purpose: Methylene blue (MB) has been used to increase blood pressure in patients with septic shock by acting on guanylate cyclase and nitric oxide synthase.

Objective: To determine whether the administration of MB to patients in the initial phase of septic shock leads to a reduction in the use of vasopressors compared to the Control group.

Methods: This was a 1:1 randomized clinical trial of two groups (MB and Control).

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