Publications by authors named "F Bazzoli"

Background: non-bismuth sequential therapy (SEQ) was suggested as a first-line anti- treatment alternative to standard triple therapy (STT).

Methods: We conducted a systematic review with a meta-analysis of randomized controlled trials (RCTs) comparing the efficacy of 10-day SEQ vs. STT (of at least 7 days) using bibliographical searches up to July 2021, including treatment-naïve adult or children.

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Article Synopsis
  • - The study aimed to assess how effectively faecal calprotectin can differentiate between inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), considering that their symptoms often overlap.
  • - Researchers reviewed data from 17 studies including nearly 2,000 patients, finding that faecal calprotectin had a sensitivity of 85.8% and specificity of 91.7%, indicating it can be a reliable diagnostic tool.
  • - The results showed that faecal calprotectin performed better in Western countries and at lower cut-off levels (≤50 μg/g), although most studies analyzed had a high risk of bias.
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(1) Background: Whether standard bismuth quadruple therapy (BQT) is superior to concomitant therapy for the first-line treatment of infection is unclear. The aim of this systematic review and meta-analysis was to compare the efficacy of standard BQT versus concomitant therapy for eradication in subjects naïve to treatment. (2) Methods: Online databases were searched for randomized controlled trials.

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Helicobacter pylori remains a major health problem worldwide, causing considerable morbidity and mortality due to peptic ulcer disease and gastric cancer. The burden of disease falls disproportionally on less well-resourced populations. As with most infectious diseases, the largest impact on reducing this burden comes from improvement in socioeconomic status, which interrupts transmission.

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