Publications by authors named "F Barker"
Article Synopsis
- - The study focused on the impact of HIV and antiretroviral therapy (ART) on kidney health in West Africans, specifically looking at people receiving ART in central Ghana from 2003 to 2018, highlighting concerns over chronic kidney disease (CKD).
- - Researchers examined data from 659 adults, finding that the use of tenofovir disoproxil fumarate (TDF) was linked to the highest decline in kidney function, while negative hepatitis B (HBsAg) status also correlated with increased eGFR decline.
- - Overall, the findings suggest that specific ART drugs like TDF, nevirapine, and certain protease inhibitors contribute to faster declines in kidney function among people living with
Article Synopsis
- This study analyzes the return-to-work (RTW) rates of patients who underwent surgery for cervical spondylotic myelopathy (CSM) as part of a larger clinical trial comparing different surgical methods.
- Of the 163 patients studied, 68 were employed before surgery, with 66% successfully returning to work within 12 months; the time it took to return varied by surgical type, with laminoplasty (LP) being the quickest.
- The analysis found that a longer hospital stay negatively impacted RTW likelihood, and patients undergoing posterior cervical decompression/fusion (PCDF) reported worse physical outcomes compared to those who had anterior cervical decompression/fusion (ACDF) and LP.
Delays and risks associated with neurosurgical biopsies preclude timely diagnosis and treatment of central nervous system (CNS) lymphoma and other CNS neoplasms. We prospectively integrated targeted rapid genotyping of cerebrospinal fluid (CSF) into the evaluation of 70 patients with CNS lesions of unknown cause. Participants underwent genotyping of CSF-derived DNA using a quantitative polymerase chain reaction-based approach for parallel detection of single-nucleotide variants in the MYD88, TERT promoter, IDH1, IDH2, BRAF, and H3F3A genes within 80 minutes of sample acquisition.
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- Survival rates for glioblastoma IDH wild-type (GBM) vary, emphasizing the need for improved surgical strategies, particularly given that most recurrences occur close to the resection margin.
- A predictive model was created to determine which GBMs could achieve radiographic gross-total resection (GTR), showing strong accuracy in forecasting surgical outcomes based on tumor characteristics.
- Analysis of surgical margins using a rapid method revealed that patients with undetected TERT promoter mutations after GTR had significantly better survival rates compared to those with detectable mutations.
Dispersal events offer a unique window into macroevolutionary processes, especially with respect to the effects of competition on diversification. Empirical studies testing alternative predictions of competitive effects are often limited in either geographic or phylogenetic scale. Here, we tested some of these hypotheses by comparing an assemblage of 16 oscine passerine clades, representing independent dispersal events into the Western Hemisphere, to their sister clades in the Eastern Hemisphere.
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