Publications by authors named "F Bakir"
Background: An innovative solution has been recently proposed for the treatment of heart failure with preserved ejection fraction (HFpEF), using a centrifugal mechanical circulatory support (MCS) device. We sought firstly to assess the hemocompatibility of the proposed device. HFpEF treatment requires the blood pump to operate at low blood flow rate (0.
View Article and Find Full Text PDFBlood pumps, critical components in ventricular assist devices and extracorporeal membrane oxygenation systems, are primarily evaluated based on their ability to minimize blood damage through optimized design. Despite extensive research, the impact of impeller blade thickness and the proximity of rotating and stationary surfaces remains insufficiently explored. This study presents a comprehensive analysis, combining experimentally validated numerical simulations with an advanced Lagrangian approach, to compare the hemodynamic and hemolytic performance of three centrifugal pumps.
View Article and Find Full Text PDFContext: Injury and functional disorders in pituitary gland after COVID-19 still need elucidation.
Objective: To investigate pituitary functions, particularly hypothalamic pituitary adrenal (HPA) axis after COVID-19 infection.
Methods: This study was conducted at a university hospital between May and October 2021.
Article Synopsis
- A new continuous flow mini pump has been created to help improve conditions for patients with Heart Failure with Preserved Ejection Fraction (HFpEF), for which no current treatments exist.
- The pump works by discharging a limited amount of blood from the left atrium to the subclavian artery, aimed at enhancing blood flow.
- The article details the pump's design, performance testing through in vitro circulation loops, computer simulations, and compares two pump configurations based on hemocompatibility indicators.
In this study, in-vitro experiments were performed to investigate the drug release from a single strut of a drug-eluting stent with respect to the systolic-diastolic flow and the continuous flow. Regarding, a test bench comprising a single strut and agarose gel as an arterial wall model was designed. The model chosen represents a large-scaled strut of a stent, to limit the effect of the geometrical shape of the stents on the drug release results.
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