Publications by authors named "F Badia-Boungou"
Article Synopsis
- Enteroviruses (EVs) affect millions each year, causing a range of illnesses from mild to severe, including dilated cardiomyopathy.
- The connection between EV infections and type 1 diabetes mellitus (T1DM) is debated, with differing opinions on the strength of the correlation and the need for more research.
- While some countries like the USA and Finland have extensive studies on this relationship, regions like MENA remain underexplored despite high T1DM prevalence, prompting a need for investigation into EVs' role in the disease in these areas.
Article Synopsis
- * Seven plants were identified, and their extracts were tested for antienteroviral activity, revealing only the aqueous extract of Syzygium brazzavillense showed significant inhibitory effects on certain viruses at specific concentrations.
- * The study concludes that aqueous extracts of Syzygium brazzavillense have potential as a treatment against enterovirus infections, highlighting its efficacy in inhibiting virus replication in vitro.
Aims: Enteroviruses, especially coxsackieviruses B (CV-B), have been associated with the pathogenesis of type 1 diabetes (T1D). An anti-CV-B4 neutralizing activity in saliva of T1D patients was previously reported. Our aim was to study the association between the saliva anti-CV-B4 neutralizing activity and immune parameters in T1D patients in comparison with non-diabetic individuals.
View Article and Find Full Text PDFMarker of coxsackievirus-B4 infection in saliva of patients with type 1 diabetes.
Diabetes Metab Res Rev
October 2017
Background: Coxsackieviruses B (CV-B) are enteroviruses that have been reported to play a role in the pathogenesis of type 1 diabetes. Enteroviral RNA was detected in the gut mucosa of patients. The mucosal immunity is an interconnected network; therefore, the response to enteroviruses possibly present in the gastrointestinal mucosa can be reflected by specific antibodies in the saliva.
View Article and Find Full Text PDFThe role of enteroviruses in type 1 diabetes has long been suspected. A lower risk of type 1 diabetes is associated with breastfeeding, which could be due to a protective effect against enteroviruses. The neutralizing activity of breast milk against CVB4, a representative of enteroviruses was investigated in this study in vitro.
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