Publications by authors named "F B Krohn"
Introduction: The Locus Coeruleus (LC) is linked to the development and pathophysiology of neurodegenerative diseases such as Alzheimer's Disease (AD). Magnetic Resonance Imaging based LC features have shown potential to assess LC integrity in vivo.
Methods: We present a Deep Learning based LC segmentation and feature extraction method: ELSI-Net and apply it to healthy aging and AD dementia datasets.
The locus coeruleus (LC) is a small brainstem structure located in the lower pons and is the main source of noradrenaline (NA) in the brain. Via its phasic and tonic firing, it modulates cognition and autonomic functions and is involved in the brain's immune response. The extent of degeneration to the LC in healthy ageing remains unclear, however, noradrenergic dysfunction may contribute to the pathogenesis of Alzheimer's (AD) and Parkinson's disease (PD).
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- Respiration is critical for life, regulated by the brain to meet metabolic demands, coordinating breathing with body movement and posture.
- * The brainstem central pattern generator works within a larger network that includes the cerebellum, which plays a key role in coordinating motor control and autonomic functions.
- * This review explores the anatomical and functional interactions of brain regions in respiratory control, the impact of sensory feedback, and how disorders can disrupt these mechanisms.
Previously, we scrutinized the dielectric spectra of a binary glass former made by a low-molecular high-T component 2-(m-tertbutylphenyl)-2'-tertbutyl-9,9'-spirobi[9H]fluorene (m-TPTS; T = 350 K) and low-T tripropyl phosphate (TPP; T = 134 K) [Körber et al., Phys. Chem.
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