Vaccination Strategies for Ebola in the Democratic Republic of Congo: The WHO-Ebola Modeling Collaboration.

Objectives: Assess the effectiveness of ring vaccination in controlling an Ebola virus outbreak in the Democratic Republic of Congo.

Methods: This analysis focuses on two areas of the Democratic Republic of Congo, Beni and Butembo/Katwa, which were affected during the 2018-2020 Ebola outbreak. To simulate Ebola virus transmission, we used a spatially explicit agent-based model with households, health care facilities, and Ebola treatment units.

Plasma-aided direct printing of silver nanoparticle conductive structures on polydimethylsiloxane (PDMS) surfaces.

We report a controlled deposition process using atmospheric plasma to fabricate silver nanoparticle (AgNP) structures on polydimethylsiloxane (PDMS) substrates, essential for stretchable electronic circuits in wearable devices. This technique ensures precise printing of conductive structures using nanoparticles as precursors, while the relationship between crystallinity and plasma treatment is established through X-ray diffraction (XRD) analysis. The XRD studies provide insights into the effects of plasma parameters on the structural integrity and adhesion of AgNP patterns, enhancing our understanding of substrate stretchability and bendability.

The toxicity of lead on human neuroblastoma cells was alleviated by HUC-MSC-derived exosomes through miR-26a-5p/PTEN pathway.

Lead is a ubiquitous environmental chemical with various toxic damage to human body. This investigation aimed to explore the intervention effect of human umbilical cord mesenchymal stem cells derived exosomes (HUC-MSC-exo) on the neurotoxicity of lead and the relevant mechanism. Differential gradient ultracentrifugation was adopted to isolate HUC-MSC-exo.