Publications by authors named "F Azizi Jalilian"
Investigating the Prevalence of Bacterial Infections in Patients with Coronavirus Disease 2019 Hospitalized in Intensive Care Unit and Determining their Antibiotic Resistance Patterns.
Infect Disord Drug Targets
November 2024
Background: COVID-19 patient hospitalization, particularly in intensive care units, exposes them to bacterial and fungi co-infections, which can have very serious consequences, including increased mortality. In addition, antibiotic resistance among pathogens is a hidden threat behind COVID-19.
Methods: In the period from 2020 September to 2021 August, bacterial isolates from COVID-19 patients admitted to the ICU of Sina Hospital in Hamadan, Iran, were collected and identified based on standard biochemical tests.
Article Synopsis
- The study investigates the presence of West Nile virus (WNV) in mosquitoes in Hamedan, Iran, where the virus is known to circulate but its mosquito vectors are not fully understood.
- Researchers collected a total of 3,243 mosquitoes from different habitats and identified seven WNV-positive pools, mainly in the species Culiseta longiareolata and Culex hortensis, indicating that WNV is actively circulating in the area.
- The findings highlight the need for further research on local WNV transmission dynamics and vector variations across different regions in Iran, providing essential information to shape prevention strategies.
Background: This in vitro study aimed to investigate the effect of several phenolic compounds, including doxorubicin, quercetin, and resveratrol, on HSV-1 infection.
Methods: The cytotoxicity of the drugs was assessed on Vero cells using the MTT assay. HSV-1 was treated with the drugs, and the supernatants were collected at various time points.
Introduction: Curcumin is known as a bioactive component that is found in the rhizomes of Curcuma longa. Curcumin is well known for its chemo-preventive and anticancer properties. However, its anticancer mechanism in colorectal cancer treatment is unclear, and some studies have shown that many microRNAs (miRs) could be potential targets for curcumin in colorectal cancer (CRC) treatment, so there is a need for their integration and clarification.
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- Human endogenous retroviruses (HERV) represent ancient viral infections integrated into our DNA, making up about 8% of the human genome, and have been linked to various diseases, including schizophrenia.
- The study registered at PROSPERO and followed systematic review guidelines analyzed 13 studies with nearly 1,500 participants, finding a strong statistical link between HERV-W and schizophrenia, especially related to specific HERV-W proteins or RNA.
- The conclusion emphasizes the need for further research to explore how HERV-W affects schizophrenia and its potential for diagnostic and treatment purposes.