Publications by authors named "F Atzori"
Prognostic Impact of IMDC Category Shift From Baseline to Nivolumab Initiation in Metastatic Renal Cell Carcinoma: A Sub-Analysis of the MEET-URO 15 Study.
Clin Genitourin Cancer
November 2024
Article Synopsis
- The IMDC score is crucial for predicting outcomes and guiding treatment in patients with metastatic renal cell carcinoma (mRCC), especially when starting therapy with nivolumab.
- A multicenter study analyzed 492 mRCC patients to see how changes in IMDC categories affected their overall survival (OS) and progression-free survival (PFS) after starting nivolumab.
- Results indicated that patients maintaining or improving their IMDC category had better survival outcomes compared to those whose condition worsened, highlighting the importance of IMDC monitoring in mRCC treatment.
Article Synopsis
- Microplastics (MPs) are polluting marine environments and may disrupt key processes in sediments, impacting the overall health of benthic ecosystems.
- A study exposed marine sediments to a mix of common MPs over 30 days and found altered organic matter composition, including a decrease in lipids and an increase in proteins.
- Results showed that contaminated sediments experienced reduced carbon degradation rates and changes in enzymatic activities, indicating MPs can significantly affect marine sediment biogeochemistry and potentially harm benthic food webs.
Introduction: Breast cancer is the most diagnosed tumor and a leading cause of cancer death in women worldwide. Taxanes are the most used chemotherapeutic agents and are strictly connected to neurotoxicity. Taxane-induced neuropathy (TIN) significantly impacts patients' quality of life (QOL).
View Article and Find Full Text PDFBackground: Young women with breast cancer (BC) have an increased chance of carrying germline BRCA pathogenic variants (PVs). Limited data exist on the prognostic impact of tumor histology (i.e.
View Article and Find Full Text PDFTo define the prognostic significance of first-line TKI in mRCC patients receiving nivolumab. A total of 571 mRCC patients who received ≥second line nivolumab were included in this subanalysis. The correlation between prior TKI (sunitinib vs.
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