Neonatal haemostatic parameters in correlation to gestational age and birth weight.

Introduction: The aim of our study was to establish reference ranges for neonatal coagulation and fibrinolysis parameters and to investigate their relationship with gestational age (GA) and birth weight (BW).

Methods: A single-centre prospective study was conducted in all healthy neonates born in our hospital during the study period, excluding those with maternal or neonatal disorders and diseases that affect haemostasis. The following parameters were measured: fibrinogen, prothrombin time (PT), international normalized ratio (INR), activated partial thromboplastin time (aPTT) as well as factors II, V, VII, VIII, IX, X, XI and XII, von Willebrand (vWF), protein C, free protein S, antithrombin (AT), activated protein C resistance (APCr), tissue plasminogen activator (tPA) and plasminogen activator inhibitor-1 (PAI-1).

Associations of Apolipoprotein A, High-Sensitivity C-Reactive Protein and Fasting Plasma Insulin in Obese Children With and Without Family History of Cardiovascular Disease.

Background: The worldwide prevalence of childhood obesity has increased from 4.2% to 6.7% during the last two decades.

Atrial septal aneurysms in childhood: prevalence, classification, and concurrent abnormalities.

Objectives: This study sought to investigate the prevalence of atrial septal aneurysms in the paediatric population and to define coexisting abnormalities and their incidence.

Background: Few papers refer to the prevalence of atrial septal aneurysms in childhood.

Methods: We enrolled a total of 4522 children aged more than 12 months who underwent a transthoracic echocardiography.