Publications by authors named "F Ashoori"
Allergic fungal rhinosinusitis linked to other hyper-IgE syndromes through defective T17 responses.
J Allergy Clin Immunol
November 2024
Article Synopsis
- A study found that the antimicrobial peptide histatin 1 (HTN1) was significantly downregulated in sinus samples from patients with allergic fungal rhinosinusitis (AFRS) compared to those with non-AFRS chronic rhinosinusitis.
- Researchers aimed to understand why HTN1 was downregulated by analyzing various immune responses and signaling pathways.
- The results revealed that AFRS patients have impaired IL-6/STAT3 signaling affecting T17/T22 cell differentiation, leading to lower levels of IL-17/IL-22 cytokines and AMPs, suggesting potential therapies to boost AMP production in these patients.
Article Synopsis
- The study focuses on improving the emulsifying ability of SA01-OmpA, a protein that previously faced issues like low production efficiency and high costs due to inclusion body formation.
- Researchers explored truncated forms of the protein to enhance its activity while reducing toxicity and the likelihood of forming inclusion bodies.
- The findings reveal that the N-terminally truncated SA01-OmpA variant significantly increases emulsifying activity and is less cytotoxic compared to the full-length protein, advancing both the understanding and application of this bioemulsifier.
Background: Needle stick injuries (NSI) can lead to dangerous infectious diseases for health care workers. This study aimed to determine the predictors of observance of safe injection guidelines in hospital nursing staff, based on protection motivation theory.
Methods: This cross-sectional study was conducted on the nursing staff of five randomly selected teaching and general hospitals of Shiraz University of Medical Sciences, Fars province, Iran, in 2021.
Background: Drug resistance in cancer cells is a major concern in chemotherapy. Cisplatin (CIS) is one of the most effective chemotherapeutics for ovarian cancer. Here, we investigated an experimental approach to increase CIS cytotoxicity and overcome cell resistance using nanoparticle-based combination treatments.
View Article and Find Full Text PDFBackground: Oral diseases are considered an important health challenge around the world, especially among children. This study aimed to compare the effects of mothers and students' education on female students' oral health behaviours.
Methods: This three-arm randomized controlled educational trial was conducted on 261 fifth- and sixth-grade female students.