Publications by authors named "F Araneda"
This work proposes the development of a starch-based drug carrier for fluoxetine (FLX) delivery and evaluate the improvement of the drug antibacterial activity. The starch nanocapsules were prepared via interfacial polyaddition reaction presenting a core-shell morphology, based on polyurethane linkage, with a particle size in the range 250-300 nm. Furthermore, FLX-loaded nanocapsules were evaluated regarding antibacterial potential against Staphylococcus aureus (ATCC® 6538P ™) and its clinical strains of methicillin-resistant.
View Article and Find Full Text PDFNanoparticles can be used in a large variety of applications, including magnetic sensing, biological, superconductivity, tissue engineering, and other fields. In this study, we explore the fabrication of gas phase silver nanoparticles using a sputtering evaporation source. This setup composed of a dual magnetron cluster source holds several advantages over other techniques.
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- Ventricular arrhythmias, linked to sudden cardiac death, are more prevalent in obese individuals, with a study showing that a high-fat diet (HFD) leads to obesity and increased arrhythmias in mice.
- The research found that RyR2 calcium release channels in the hearts of obese mice were more active and altered at the molecular level, indicating redox modifications due to fewer free thiol residues.
- Administering apocynin to the HFD-fed mice not only prevented arrhythmias but also normalized RyR2 activity and thiol content, highlighting a redox-dependent mechanism as a key factor in the increased arrhythmias associated with obesity.
Background: Persistent hyperlactatemia is particularly difficult to interpret in septic shock. Besides hypoperfusion, adrenergic-driven lactate production and impaired lactate clearance are important contributors. However, clinical recognition of different sources of hyperlactatemia is unfortunately not a common practice and patients are treated with the same strategy despite the risk of over-resuscitation in some.
View Article and Find Full Text PDFBackground: Vaginal infection is the commonest cause of genital symptoms and has obstetric and gynecological implications.
Aim: To compare the Nugent and Spiegel methods for the diagnosis of bacterial vaginosis (BV) and to analyze discordant specimens using Ison and Hay (Ison/Hay) criteria.
Material And Methods: After discarding cases with Candidiasis, deficient specimens or those lacking bacteria, a total of 348 Gram-stained smears vaginal specimens received for the diagnosis of BV, were analyzed.