Publications by authors named "F Arai"

Cybernetic avatars integrate physical and virtual avatars to enhance human capabilities in diverse scales and contexts.

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Article Synopsis
  • A Rare Cell Sorter (RCS) was tested in a pilot study to collect circulating tumor cells (CTCs) from lung cancer patients and verify their authenticity by comparing EGFR mutation status with tissue samples.
  • The study involved 18 patients, with CTCs found in 6 (33%), and a significant concordance of 83% for EGFR mutations between CTCs and tissue samples, achieving a high overall concordance rate of 96%.
  • The results demonstrate that the RCS can effectively detect CTCs and suggests its potential for broader applications in cancer detection, although larger studies are needed for further validation.
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Purpose: To construct a quantitative evaluation system for hand tremor during internal limiting membrane (ILM) peeling and investigate changes in hand tremor attributable to the use of the customized passive surgical support robot.

Methods: This analytical and experimental study developed a hand tremor evaluation system that synchronizes three elements: surgical microscope images, an artificial eye module with a force sensor to simulate ILM peeling, and microforceps with an inertial measurement unit. Two surgeons used this system to measure hand tremor during ILM peeling with and without the robot.

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Microvortices are emerging components that impart functionality to microchannels by exploiting inertia effects such as high shear stress, effective fluid diffusion, and large pressure loss. Exploring the dynamic generation of vortices further expands the scope of microfluidic applications, including cell stimulation, fluid mixing, and transport. Despite the crucial role of vortices' development within sub-millisecond timescales, previous studies in microfluidics did not explore the modulation of the Reynolds number (Re) in the range of several hundred.

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Metal-free room-temperature phosphorescent (RTP) materials are attracting attention in such applications as organic light-emitting diodes and bioimaging. However, the chemical structures of RTP materials reported thus far are mostly predominantly based on π-conjugated systems incorporating heavy atoms such as bromine atoms or carbonyl groups, resulting in limited structural diversity. On the other hand, triarylboranes are known for their strong Lewis acidity and deep LUMO energy levels, but few studies have reported on their RTP properties.

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