Publications by authors named "F Antillon-Klussmann"
Nudix hydrolase 15 (NUDT15) deficiency is strongly associated with thiopurine-induced myelosuppression. Currently, testing for NUDT15 deficiency is based on the genotyping of the most frequent and clinically characterized no-function variants, that is, *2, *3 and *9. The Hispanic/Latino-predominant variant NUDT15 *4 (p.
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- The study explores how caregivers of children with cancer in Guatemala City understand illness through Explanatory Models (EMs) during clinical interactions at Unidad Nacional de Oncología Pediátrica (UNOP).
- It involved analyzing audio recordings and interviews from caregivers to identify how the EM components—cause, occurrence, pathophysiology, course of sickness, and treatment—were discussed in the diagnostic process.
- The findings revealed that while clinicians often initiated EM discussions, caregivers engaged with most components, particularly focusing on personal illness experiences rather than technical aspects like pathophysiology, highlighting the importance of culturally-competent communication in pediatric oncology care.
Background: Cancer is the fourth leading cause of death in adolescents and young adults (AYA) worldwide. Although successful treatment of cancer in AYA has increased in recent years in most of the world, this is not true for many low- and middle-income countries (LMIC) where over 80% of all AYA live. This study investigated the needs of AYA with cancer in parts of Latin America (LATAM) through the perspectives of non-physician health care providers and partners.
View Article and Find Full Text PDFThe TeLeo Program offers a free-access 2-year online learning program to support fellowship programs in pediatric oncology, enhance networking opportunities, and facilitate the exchange of context-specific, educational content within the pediatric oncology community in training in Latin America. In its first edition beginning in 2021, 185 fellows from 40 centers in 12 Latin American countries were enrolled. Additional courses for other healthcare professionals related to oncology in the region were produced to further support the program.
View Article and Find Full Text PDFBackground: Effective communication is founded on bidirectional participation from families and healthcare providers. In adult medicine, bidirectional communication promotes treatment adherence and builds the family-provider relationship. However, the relationship between communication styles in pediatrics remains poorly understood, particularly in culturally diverse settings.
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