Effect of microencapsulated Fiber2-displaying probiotics loaded with inulin nanoparticles on immunity against fowl adenovirus serotype 4 in chickens.

In this study, phthalate inulin nanoparticles (PINs) were chemically modified and characterized. The internalization of PINs into the probiotic E. faecalis, which delivering Fiber2 protein of fowl adenovirus serotype 4 (FAdV-4), was investigated.

Excitation wavelength-dependent quantum yield in water-soluble CdTe quantum dots.

The quantum yield (QY) of semiconductor quantum dots (QDs) is severely hampered by the inherent fluorescence intermittency. The QY of QDs typically increases with an increase in the excitation wavelength. Here, we present a distinctive behavior, where the QY is found to decrease with an increase in the excitation wavelength in water-soluble CdTe QDs (CQDs).

Honey bee inspired resource allocation scheme for IoT-driven smart healthcare applications in fog-cloud paradigm.

The Internet of Things (IoT) paradigm is a foundational and integral factor for the development of smart applications in different sectors. These applications are comprised over set of interconnected modules that exchange data and realize the distributed data flow (DDF) model. The execution of these modules on distant cloud data-center is prone to quality of service (QoS) degradation.

Exploring PDK3 inhibition in lung cancer through drug repurposing for potential therapeutic interventions.

The pyruvate dehydrogenase kinase-3 (PDK3) plays an important role in the regulation of a variety of cancers, including lung, by inhibiting the pyruvate dehydrogenase complex (PDC), shifting energy production towards glycolysis necessary for cancer metabolism. In this study, we aimed to identify potential PDK3 inhibitors using a computer-based drug design approach. Virtual screening of the FDA-approved library of 3839 compounds was carried out, from which Bagrosin and Dehydrocholic acid appeared best due to their strong binding affinity, specific interactions, and potential biological characteristics, and thus were selected for further investigations.