Publications by authors named "F Anglada-Curado"
Article Synopsis
- Active surveillance (AS) is a strategy used to monitor low-risk prostate cancer patients, but the effectiveness of multiparametric MRI (mpMRI) in this context is not well defined.
- A study involving 229 patients evaluated mpMRI's role in detecting significant prostate cancer and found that suspicious mpMRI results were linked to a higher reclassification and disease progression risk.
- Results indicated that over time, patients with more concerning mpMRI findings had higher rates of progression, highlighting mpMRI's potential in guiding treatment decisions during AS protocols.
PSA is the most widely used diagnosticand prognostic biomarker in prostate cancer (PCa).However, its lack of specificity has generated the needto search for new complementary markers. In thisscenario, blood plasma constitutes one of the sourcesof search for new markers, which have been tried tobe combined with PSA and other clinical variables inorder to develop tests that increase their diagnosticspecificity.
View Article and Find Full Text PDFDoes Adding Standard Systematic Biopsy to Targeted Prostate Biopsy in PI-RADS 3 to 5 Lesions Enhance the Detection of Clinically Significant Prostate Cancer? Should All Patients with PI-RADS 3 Undergo Targeted Biopsy?
Diagnostics (Basel)
July 2021
Article Synopsis
- - The study aimed to evaluate the added value of standard biopsy alongside targeted biopsy for cases with suspicious mp-MRI results, particularly analyzing when to skip biopsying PI-RADS 3 lesions.
- - Data from 483 biopsies revealed that while standard biopsy improved detection rates of clinically significant prostate cancer (csPCa) in specific groups, it was less effective for PI-RADS-5 lesions and in patients with a prior negative biopsy.
- - Conclusions indicate that standard biopsy can likely be avoided for patients with anterior lesions and PI-RADS-5 lesions, while targeted biopsy for PI-RADS-3 lesions is more effective in specific patient categories, particularly biopsy-naïve individuals.
Objective: To describe the technique of transrectal biopsy with a new device that fuses multiparametric magnetic resonance (mpMRI) and ultrasound images in real time to guide target biopsies and to evaluate our initial experience.
Methods: Patients with persistent suspicion of prostate cancer despite a previous negative biopsy and who had an mpMRI before the biopsy were selected. All patients underwent target biopsy plus standard systematic biopsy.
Purpose: Simultaneous pancreas-kidney transplantation is the gold standard treatment for patients with end-stage renal failure secondary to insulin-dependent diabetes mellitus. This kind of transplantation is a complex operation associated with a high incidence of surgical complications and mortality risk which could influence graft survival. The aim of this study was to establish the influence of different grades of postoperative complications, classified according to Clavien-Dindo, on the rate of kidney graft loss.
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