Publications by authors named "F Alpiste-Illueca"
Article Synopsis
- The study investigates miRNAs in the gingival crevicular fluid (GCF) of chronic periodontitis patients to identify potential biomarkers for the disease.
- GCF samples were collected from patients with advanced chronic periodontitis and healthy subjects, and various miRNAs were sequenced and analyzed for expression levels.
- The results highlighted miR-199 as the most significant biomarker for periodontitis, suggesting that miRNA profiling in GCF could enhance understanding and diagnosis of periodontal disease.
MicroRNAs and periodontal disease: a qualitative systematic review of human studies.
J Periodontal Implant Sci
December 2021
Purpose: MicroRNAs (miRNAs) are epigenetic post-transcriptional regulators that modulate gene expression and have been identified as biomarkers for several diseases, including cancer. This study aimed to systematically review the relationship between miRNAs and periodontal disease in humans, and to evaluate the potential of miRNAs as diagnostic and prognostic biomarkers of disease.
Methods: The review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines (reference number CRD42020180683).
Invasive cervical resorption (ICR) is an uncommon phenomenon (0.1%), however, it represents a challenge to the structural and functional integrity of the dentogingival junction, as well as a risk for the survival of the affected tooth. They are characterized by their location and invasive character, being able to appear in any tooth of the permanent dentition.
View Article and Find Full Text PDFAim: Alveolar resorption is one of the most important events in periodontitis. Osteoclast activity is regulated by the ratio between receptor activator of NF-κB ligand (RANKL) and osteoprotegerin (OPG). The aim of this study was to evaluate changes in the RANKL/OPG ratio in crevicular fluid after periodontal treatment.
View Article and Find Full Text PDFBackground: This study aimed to analyze the efficacy of an anti-calculus mouth rinse and its possible adverse effects on the mucosa and teeth.
Material And Methods: This randomized double-blind placebo-controlled clinical trial included 40 patients with treated and managed periodontal disease, all with a history of rapid calculus formation. Patients used a pyrophosphate-based test mouth rinse (B) or a placebo (A).