Publications by authors named "F Alper"
Limited advancements in managing malignant brain tumors have resulted in poor prognoses for glioblastoma (GBM) patients. Standard treatment involves surgery, radiotherapy, and chemotherapy, which lack specificity and damage healthy brain tissue. Boron-containing compounds, such as boric acid (BA), exhibit diverse biological effects, including anticancer properties.
View Article and Find Full Text PDFComparison of methotrexate and methylprednisolone as addition to antifibrotic therapy in progressive pulmonary fibrosis due to COVID-19.
Sarcoidosis Vasc Diffuse Lung Dis
December 2024
Background: Post-covid pulmonary fibrosis (PCPF) is an essential cause of hypoxic respiratory failure, especially in patients with severe COVID-19 infection. In our study, we aimed to compare the effectiveness of methylprednisolone and methotrexate treatments in patients diagnosed with PCPF and in whom progression was observed despite nintedanib treatment. Methods: Forty-eight patients diagnosed with PCPF between April 2022 and February 2023 were followed up in our study.
View Article and Find Full Text PDFArticle Synopsis
- Gadolinium deposition in rat kidneys was studied following single and multiple doses, aiming to see how long it lasts and if there's a link between deposition levels and T1-weighted image intensity.
- The study involved 70 rats divided into groups receiving varying doses, with assessments made at different time points using imaging and mass spectrometry.
- Results showed more injections led to higher gadolinium levels, but there was little difference between low and medium doses, and T1 intensity measurement was found to be unreliable for gauging deposition.
Objectives: The aim of this study is to present novel diagnostic ultrasonography (USG)-based classification of inflammatory granulomatous mastitis (IGM) and to assess and compare dosage responses of locoregional steroid therapy.
Methods: From January 2017 through March 2023, total of 230 biopsy-proven IGM patients were reclassified (grades I, II, and III) according to USG-based morphological features. The injection applications were grouped in Group1 (40 mg/mL between years 2017 and 2019) versus Group2 (80 mg/mL between years 2019 and 2023), and effectiveness was analysed for each grade in between groups.