Publications by authors named "F Alfano"

Article Synopsis
  • Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with unknown causes, linked to vascular abnormalities and complications like pulmonary hypertension (PH).*
  • A literature review reveals crucial molecular mechanisms involved in vascular changes related to IPF, emphasizing their potential as prognostic markers and highlighting the impact of antifibrotic therapies.*
  • The findings suggest that the vasculature is integral to IPF's progression and that emerging treatments with a vascular focus may improve outcomes for patients.*
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Article Synopsis
  • The study examined 91 exotic companion mammals from pet shops in southern Italy for the presence of eight potential zoonotic viruses using advanced PCR techniques.
  • Only one rat tested positive for aichivirus, which showed a close genetic relationship to a strain identified in China, indicating possible introduction from Asia.
  • Continuous monitoring of these animals is essential to prevent the spread of pathogens to humans and domestic animals, emphasizing the need for further research on zoonotic viruses.
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Introduction: Patients with central neoplasms and haemoptysis show low survival rates. Symptom control without recurrence 48 h after bronchoscopic interventions may improve the prognosis of these patients. Bronchoscopic argon plasma coagulation (APC) is a useful technique for endobronchial management of haemoptysis in patients with central malignancies.

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Respiratory syncytial virus (RSV) infection represents one of the most common infections during childhood, with significant morbidity and mortality in newborns and in the early years of life. RSV is a common infection throughout all age groups, largely undetected and underestimated in adults, with a disproportionately high impact in older individuals. RSV infection has a wide range of clinical presentations, from asymptomatic conditions to acute pneumonia and severe life-threatening respiratory distress, including exacerbations of underlying chronic conditions.

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Introduction: N-acetylcysteine (NAC) is a mucolytic agent with antioxidant properties. Oxidative stress is a key pathogenic mechanism in chronic respiratory conditions such as COPD and chronic bronchitis (CB). In these meta-analyses we investigated the efficacy of NAC in subjects with COPD or CB, the latter being a potential pre-COPD condition (CB/pre-COPD).

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