Publications by authors named "F Aldakheel"

Background: Asthma is considered one of the most common and serious noncommunicable diseases, with high morbidity and mortality rates in both children and adults.

Objectives: To estimate the frequency and to determine the associated factors of self-reported asthma among children diagnosed with type 1 diabetes.

Methods: A cross-sectional study design was employed, and 175 subjects having type 1 diabetes for more than 1 year were included from the pediatrics endocrine clinic.

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  • * Mitochondrial dysfunction plays a crucial role in HF, particularly through issues with calcium homeostasis and oxidative stress, which worsen the condition.
  • * This review highlights the need for more research on mitochondrial dynamics and oxidative stress in different HF types, and it calls for the development of new treatments targeting these mitochondrial issues to improve patient outcomes.
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  • Atrial fibrillation (AF) is a common heart condition linked to serious complications like stroke and heart failure, and recent studies suggest that an imbalance in gut bacteria may play a significant role, especially in older adults.
  • The review explores how gut microbiota and their byproducts might trigger AF and stresses the need for more research on the connection between gut health and heart function, which is often overlooked.
  • Future studies should focus on the gut microbiome's impact on AF and consider using probiotics or prebiotics as part of treatment, potentially leading to innovative ways to improve patient care by connecting heart and gut health.
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Allergic asthma, a chronic inflammatory illness that affects millions worldwide, has serious economic and health consequences. Despite advances in therapy, contemporary treatments have poor efficacy and negative effects. This study investigates hematopoietic prostaglandin D2 synthase (HPGDS) as a potential target for novel asthma therapies.

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Apigenin is a powerful flavone compound found in numerous fruits and vegetables, and it offers numerous health-promoting benefits. Many studies have evidenced that this compound has a potential role as an anti-inflammatory and antioxidant compound, making it a promising candidate for reducing the risk of pathogenesis. It has also been found to positively affect various systems in the body, such as the respiratory, digestive, immune, and reproductive systems.

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