Publications by authors named "F Akgul"

Article Synopsis
  • The study aimed to evaluate how the combination of HALP score and TTCR score influences overall survival (OS) and progression-free survival (PFS) in prostate cancer patients who developed castration resistance.
  • A total of 152 metastatic prostate cancer patients were analyzed, categorized based on median cut-off values for HALP (30.83 months) and TTCR (16.1 months), resulting in three risk stratification groups.
  • The findings indicated that lower HALP scores and shorter TTCR were linked to significantly worse PFS, and that combining these factors improved predictions for OS and PFS in patients with metastatic castration-resistant prostate cancer (mCRPC).
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Extrapulmonary tuberculosis (EPTB) is an important public health problem due to its diverse clinical presentations, diagnostic complexities, and significant impact on patient outcomes and public health. Our study aimed to understand the sociodemographic, clinical, and laboratory characteristics as well as diagnostic and treatment modalities of adult patients with EPTB. This is a multicentric retrospective study that covers patients with EPTB cases followed up from January 2015 to December 2022 among tuberculosis (TB) dispensaries and Infectious Diseases and Clinical Microbiology clinics of 15 hospitals located in various regions of Turkey.

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Background: Brucellosis is one of the most common zoonotic infections. Although culture is the gold standard diagnostic method, bacterial growth in blood cultures may not always occur due to various factors. We aimed to investigate demographic, clinical, and laboratory findings that may have predictive significance for bacteremia in brucellosis.

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Article Synopsis
  • * This study analyzed the effectiveness of two treatments, pazopanib and sunitinib, in non-ccRCC patients across 22 hospitals, looking at progression-free survival, overall survival, and patient response rates.
  • * The findings suggest that pazopanib and sunitinib have similar efficacy, with specific patient characteristics affecting outcomes; pazopanib could be considered a viable treatment option alongside sunitinib and cabozantinib.
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Aim: To identify possible drug-drug interactions in patients taking medications for other comorbidities while on antiviral therapy for chronic hepatitis B.

Methods: The study enrolled patients with chronic hepatitis B aged ≥60 years who were treated with antiviral therapy in five hospitals in Turkey between January 1 and March 1, 2023. The Lexicomp® Drug Interactions program was used to identify possible drug-drug interactions.

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