Publications by authors named "F Abbasvandi"
Article Synopsis
- The study investigates the relationship between breast cancer-related lymphedema (BCRL) and sleep disturbances, particularly obstructive sleep apnea (OSA), among breast cancer survivors (BCSs).
- Using several questionnaires, the quality of sleep and OSA risk were assessed among 71 women with BCRL and 84 without it, revealing that both groups experience high levels of sleep disturbances.
- Results indicated that those with advanced BCRL stages had a higher risk for OSA, with significant correlations between BCRL stage and neck circumference, emphasizing the need for clinical monitoring of sleep issues in this population.
Clinical validation on role of cancer diagnostic probe in detecting the involved cavity margins missed in permanent pathology of tumor side in breast cancer surgery.
Diagn Pathol
November 2024
Cancer diagnostic probe (CDP) as a newly entered tool in real-time breast cavity margin evaluation showed great improvement in smart margin shaving intra-operatively. This system increased the rate of involved margin detection to 30% with respect to frozen section. In this study for the first time we showed the independent role of CDP in finding the involved cavity side margins which were not diagnosed by permananet pathology of their tumor side interface.
View Article and Find Full Text PDFArticle Synopsis
- Cancer-associated fibroblasts (CAFs) play a vital role in tumor progression and can transform adjacent normal tissue into a neoplastic state due to oxidative stress pathways, affecting breast cancer margins.
- The study used advanced biosensors to analyze the glycolytic behavior of non-tumoral margins and detect CAF accumulation, investigating the relationship between CAF presence and the neoplastic potential in surrounding tissues.
- Results showed significant increases in specific cancer-associated transcripts in glycolytic but histologically non-cancerous areas, indicating that these areas may still harbor high-risk cells influenced by CAF activity.
Lymph node (LN) status is an essential prognostic factor in breast cancer (BC) patients, with an important role in the surgical and therapeutic plan. Recently, we have been developed a novel system for real-time intra-operative electrical LN scanning in BC patients. The ELS scores were calibrated by pathological evaluation of the LNs.
View Article and Find Full Text PDFBackground: Idiopathic granulomatous mastitis (IGM) is mostly described as an autoimmune disease with higher prevalence among Middle Eastern childbearing-age women. This study aimed to evaluate the best treatment of choice in patients with resistant or recurrent IGM.
Study Design: Patients with established recurrent or resistant IGM who were referred to the Breast Cancer Research Center from 2017 to 2020 were randomly assigned to either one of the following treatment groups: A (best supportive care), B (corticosteroids: prednisolone), and C (methotrexate and low-dose corticosteroids).