Publications by authors named "F A Zantvoort"
Article Synopsis
- The Eurotransplant Kidney Allocation System considers patients with life-threatening conditions for high-urgency (HU) kidney transplants, but the effectiveness of this approach is debated due to limited data.
- A study analyzed the outcomes of 898 HU kidney transplant recipients and found they were typically younger, waited less time for a transplant, but had worse patient survival rates and higher rates of retransplantation compared to non-HU recipients.
- The findings suggest that current criteria for HU allocation should be reconsidered to prioritize patients on the non-HU waiting list who tend to have better long-term outcomes.
This ongoing multicenter prospective observational study was undertaken in de novo renal allograft recipients managed with cyclosporine (CsA) trough (C0) and 2-hour postdose (C2) level monitoring at defined times so as to assess the risk for an acute rejection episode or allograft dysfunction. The renal transplant recipients (n = 159) were enrolled at 11 German centers. The 6-month posttransplant data from 138 patients were evaluable for this interim analysis.
View Article and Find Full Text PDFAn important contribution of HLA-A antigen matching in renal transplantation was reported initially, hut later publications showed a minor or absent role. We analyzed the contribution of HLA-A locus matching to graft survival in 17,672 first renal transplants from unrelated, nonliving donors. We show that an independent HLA-A matching effect still exists.
View Article and Find Full Text PDFRenal allograft biopsy is very valuable in the assessment of graft dysfunction, but complications are frequent and graft loss has even been described. Between 1991 and 1993, a total of 133 graft biopsies were done. We used an automated biopsy gun with a fine-caliber core needle (diameter 1.
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