Publications by authors named "F A Vreju"
Clinical Efficacy and Safety of Ultrasound-Guided Injection with Low-Molecular-Weight Peptides from Hydrolyzed Collagen in Patients with Partial Supraspinatus Tendon Tears: A Pilot Study.
Life (Basel)
October 2024
Background: This study evaluates the clinical efficacy and safety of two ultrasound (US)-guided injections of a 5 mg/1 mL low-molecular-weight peptide (LWP) solution derived from hydrolyzed bovine collagen in patients with supraspinatus partial tendon tears.
Methods: A total of 21 patients with symptomatic partial tears of the supraspinatus tendon, detected by US, were consecutively enrolled and received one injection at a baseline visit (T0) and one after two weeks (T1). The primary outcome measure was the visual analogue scale (VAS) for pain.
Assessment of Neutrophil-Lymphocyte Ratio and Systemic Immune-Inflammation Index in Systemic Scleroderma Patients with Focus on Cardiopulmonary Manifestations.
Curr Health Sci J
September 2024
Objectives: To quantify levels of two inflammation-related indexes, namely neutrophil-lymphocyte ratio (NLR) and systemic immune-inflammation index (SII) in systemic scleroderma patients and determine the association with clinical manifestations and features of heart ultrasound.
Methods: The study group consisted of 34 patients with diagnosis of systemic scleroderma which were admitted to the hospital during 2015-2019. Patient data included the presence and type of clinical manifestations of systemic scleroderma, chest imaging to screen for lung disease, heart ultrasound reports and the laboratory investigations needed to quantify inflammatory indexes.
Article Synopsis
- A study involving 65 gout patients and 40 healthy individuals investigated the presence of subclinical carotid atherosclerosis, which is a risk factor for cardiovascular disease, through ultrasound examinations.
- The findings showed a significantly higher prevalence of increased carotid intima-media thickness (CCAIMT) and carotid plaques in gout patients compared to the controls, indicating a potential connection between gout and cardiovascular risks.
- Various factors, such as serum uric acid levels, age, disease duration, and low-density lipoprotein cholesterol, were found to independently contribute to the increased carotid thickness and plaque formation in gout patients, emphasizing the usefulness of carotid ultrasound as a diagnostic tool.
Article Synopsis
- The study involved 54 psoriasis (PsO) patients and 40 control subjects to investigate the prevalence of metabolic syndrome (MetS) and its link to subclinical atherosclerosis, assessed through carotid ultrasound.
- Results showed that 64.81% of PsO patients had MetS compared to only 27.5% of control patients, indicating a significant difference in metabolic health between the two groups.
- The findings also revealed a higher incidence of carotid plaque and increased intima-media thickness (IMT) in PsO patients with MetS, suggesting a strong correlation between MetS, psoriasis, and an elevated risk of cardiovascular issues.
The present study is aimed at assessing the presence and prevalence of subclinical entheseal changes in Psoriasis (PsO) patients using musculoskeletal ultrasonography (US), conjoined with the analysis of possible differences in terms of demographic, clinical, or biological features. We carried out an observational study on 54 patients with PsO and 40 controls. Subclinical enthesopathy, according to OMERACT definitions, was identified in 20 of the psoriasis patients (37.
View Article and Find Full Text PDF