An innovative Community Mobilisation and Community Incentivisation for child health in rural Pakistan (CoMIC): a cluster-randomised, controlled trial.

Background: Infectious diseases remain the leading cause of death among children younger than 5 years due to disparities in access and acceptance of essential interventions. The Community Mobilisation and Community Incentivisation (CoMIC) trial was designed to evaluate a customised community mobilisation and incentivisation strategy for improving coverage of evidence-based interventions for child health in Pakistan.

Methods: CoMIC was a three-arm cluster-randomised, controlled trial in rural areas of Pakistan.

Outcomes of 23-Gauge Pars Plana Vitrectomy in Various Vitreoretinal Diseases.

Background This study aimed to evaluate the safety, efficacy, and complications of 23-gauge (23-G) pars plana vitrectomy (PPV) in the treatment of various vitreoretinal diseases. Methodology A retrospective, cross-sectional study was conducted at Al-Shifa Trust Eye Hospital, Rawalpindi. All the eyes undergoing 23-G PPV between June 2020 and May 2023 meeting the inclusion criteria were included.

Triterpenoid saponins from the fruit pulp of (Fabaceae).

fruit, used as spice in West Africa was studied chemically; five previously undescribed triterpenoid saponins - and four known compounds - were isolated from the -Butanol fraction. The chemical structures of all nine isolates were determined by comprehensive analysis of HRMS, 1D & 2D NMR experiments and by comparison with data in the literature. All nine compounds were evaluated for antibacterial activity by the broth microdilution through the rapid -iodonitrotetrazolium chloride (INT) colorimetric technique.

Pediatric Kidney Donation and Transplantation in Kingdom of Saudi Arabia.

The evolution of pediatric kidney donation and transplantation in the Kingdom of Saudi Arabia underscores the transformative effects of strategic initiatives and institutional reforms aimed at fostering self-sufficiency and ethical stewardship in transplantation. The ascendance of the Saudi Center for Organ Transplantation as a regional hub for organ procurement and transplantation is a testament to Saudi Arabia's commitment to advancing health care delivery and promoting international collaboration in combating organ trafficking and commercialism. Moving forward, sustained investments in infrastructure, capacity building, and regulatory oversight will be paramount to addressing emerging challenges and consolidating Saudi Arabia's position as a global leader in transplantation.