The diagnosis and vector potential of Ornithonyssus bacoti tropical rat mites in northern Europe.

The mesostigmatid tropical rat mite, Ornithonyssus bacoti, is an important cause of disease in small rodents, and of gamasoidosis in humans when they come into contact with infestations. Most reports of O. bacoti infestations are from warmer parts of the Americas, southern Europe and Asia; and infection has only rarely been recorded in northern Europe.

Time-lapse mesoscopy of and dual-species biofilms reveals a structural role for the hyphae of in biofilm formation.

Polymicrobial infection with and may result in a concomitant increase in virulence and resistance to antimicrobial drugs. This enhanced pathogenicity phenotype is mediated by numerous factors, including metabolic processes and direct interaction of with hyphae. The overall structure of biofilms is known to contribute to their recalcitrance to treatment, although the dynamics of direct interaction between species and how it contributes to pathogenicity is poorly understood.

Nanoscaled Discovery of a Shunt Rifamycin from Using a Three-Color GFP-Tagged Macrophage Infection Assay.

Antimicrobial resistance has emerged as a global public health threat, and development of novel therapeutics for treating infections caused by multi-drug resistant bacteria is urgent. is a major human and animal pathogen, responsible for high levels of morbidity and mortality worldwide. The intracellular survival of in macrophages contributes to immune evasion, dissemination, and resilience to antibiotic treatment.

Faecal egg counts and nemabiome metabarcoding highlight the genomic complexity of equine cyathostomin communities and provide insight into their dynamics in a Scottish native pony herd.

Understanding the composition of gastrointestinal nematode communities may help to mitigate or exploit parasite adaptations within their host. We have used nemabiome deep amplicon sequencing of internal transcribed spacer-2 (ITS-2) ribosomal DNA to describe the temporal and host species composition of gastrointestinal nematode communities following sampling of six Scottish ponies across 57 months. In the absence of parasite control, each horse showed seasonal trends of increases and decreases in faecal egg counts, consistent with the epidemiology of equine strongylid parasites, however, the composition of parasites within individuals changed over time.