Publications by authors named "F A Raffa"

Coupled optical cavities provide one of the simplest possible schemes to engineer the interaction of bosonic modes. This paper investigates a two-mode model where, in addition to the usual mode coupling, the presence of an amplification term associated to one of the modes triggers an unexpectedly rich dynamical scenario. The resulting nontrivial model is diagonalized by implementing the dynamical-algebra method, a group-theoretic approach which allows one to determine the stability diagram of the model Hamiltonian in terms of the two mode frequencies for given values of the interaction and amplification parameters.

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Storm surges are natural events that influence the dispersion of sediment along coasts, leading to sudden morphological changes in the seabed. From this perspective, we focused our study on the analysis of measurements from a mobile X-band radar system to survey the sea state and the changes in the seabed depth during storm surges. This analysis was supported by additional information from Sentinel 2 satellite images, the , the hydrometric station, and an echosounder survey.

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Article Synopsis
  • The study focused on identifying factors that lead to nonadherence to biologic therapy in patients with inflammatory bowel disease (IBD), specifically Crohn's disease (CD) and ulcerative colitis (UC).
  • About 460 patients were evaluated, revealing that 69% adhered to their treatment, with lower adherence rates in those with CD compared to UC.
  • Key risk factors for nonadherence included having CD, being on Medicaid insurance, and having a history of psychiatric issues, smoking, or prior biologic therapy; the likelihood of nonadherence increased with the number of risk factors present.
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Background: Patients with triple negative breast cancer (TNBC) exhibit poor prognosis and are at high risk of tumour relapse, due to the resistance to chemotherapy. These aggressive phenotypes are in part attributed to the presence of breast cancer stem cells (BCSCs). Therefore, targeting BCSCs is a priority to overcoming chemotherapy failure in TNBCs.

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Dendritic cells (DC) are a promising cell type for cancer vaccines due to their high immunostimulatory capacity. However, improper maturation of DC prior to treatment may account for the limited efficacy of DC vaccine clinical trials. Latent Membrane Protein-1 (LMP1) of Epstein-Barr virus was examined for its ability to mature and activate DC as a gene-based molecular adjuvant for DC vaccines.

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