Publications by authors named "F A R Al-Lawati"

Article Synopsis
  • High rates of early-onset breast cancer (EOBC) in the Middle East, particularly in Oman, where over 50% of breast cancer patients are under 45 at diagnosis, raise questions about the causes.
  • A study of 1336 breast cancer patients in Oman from 2010 to 2022 found no significant link between BRCA1/2 gene mutations and EOBC, as most cases lacked a family history of breast cancer.
  • Despite the absence of a strong correlation with BRCA mutations, EOBC tumors exhibited distinct features like larger size, higher grade, and poorer survival outcomes compared to later-onset cases.
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Article Synopsis
  • COVID-19 led to a significant number of intubations and intensive care admissions, with many patients experiencing barotrauma, a condition where alveoli rupture and air escapes into surrounding spaces.
  • This report examines 14 COVID-19 patients who developed barotrauma, either spontaneously or after non-invasive ventilation, even those who initially had milder forms of the disease.
  • Managing barotrauma in these patients is complex and may necessitate invasive mechanical ventilation, which raises the risk of complications and mortality, highlighting the importance of lung protective measures.
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Objectives: For COVID-19-related respiratory failure, noninvasive respiratory assistance via a high-flow nasal cannula (HFNC), helmet, and face-mask noninvasive ventilation is used. However, which of these options is most effective is yet to be determined. This study aimed to compare the three techniques of noninvasive respiratory support and to determine the superior technique.

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Objectives: To identify the biochemical, hematological, and immune biomarkers in COVID-19 patients on admission that are predictive of eventual admission to the intensive care unit (ICU).

Methods: This retrospective cohort study was conducted on all confirmed COVID-19 cases hospitalized at Royal Hospital, Oman from 24 February to 30 July 2020. The demographic, clinical, and laboratory data were collected from the hospital information system.

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Objectives: To investigate the relationship between attitudes toward COVID-19 vaccines and disapproval of the policy of mandatory COVID-19 vaccination among unvaccinated physicians and nurses in Oman.

Methods: The subjects were (N = 346) unvaccinated physicians and nurses in Oman. Their demographic data and attitudes regarding COVID-19 vaccines and mandatory vaccination policy were collected through an anonymous web-based survey and statistically analyzed.

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