[Molecular-biological and antigenic features of H5N1 subtype highly pathogenic influenza virus strains isolated in southern Siberia in 2005-2009].

Aim: Study of molecular-biological and antigenic features of H5N1 subtype virus strains isolated in southern Siberia in 2005-2009.

Materials And Methods: Study was performed by using standard procedures according to WHO recommendations.

Results: Hemagglutinin gene of H5N1 subtype virus strain isolated in Siberia belongs to 2 genetical lineages: 2.

[Monitoring for influenza in population of Western Siberia in 2007-2009].

Aim: To analyze influenza viruses isolated in the 2008-2009 autumn-winter season, and to test sera collected in the south of Western Siberia during the beginning and the end of the epidemic seasons from 2007 until the A/H1N1 pandemic.

Materials And Methods: Total 149 clinical samples were analyzed and 2190 blood sera were tested. During the 2008-2009 season 17 influenza viruses were isolated.

[Isolation of influenza A virus from wild birds in western part of Mongolia].

Aim: To study circulation of influenza A viruses in western part of Mongolia.

Materials And Methods: Isolation and characterization of influenza viruses was performed according to recommendations of WHO.

Results: Circulation of influenza A viruses subtypes H3N6, H4N6, H1N1, H13N8 in different wild bird species in western part of Mongolia was documented.

Surveillance and identification of influenza A viruses in wild aquatic birds in the Crimea, Ukraine (2006-2008).

The ecology of avian influenza (AI) viruses in wild aquatic birds of Asia is poorly understood, especially for the H5N1 high pathogenicity AI (HPAI) viruses. From March 2006 through November 2008, 20 AI viruses were isolated in the Crimea region of Ukraine with an overall frequency of virus recovery of 3.3%.

[Effects of ligands of alpha2-adrenoceptors on mRNA level of apoptotic proteins in the developing rat brain].

The effects of antagonist of alpha2-adrenoceptors yohimbine and their agonist clonidine on Bax and Bcl-XL mRNA levels in neonatal rat brain were studied. Yohimbine decreased Bax mRNA level in the cerebellum, increased the ratio between Bcl-XL and Bax mRNA levels in the cerebellum, cortex, and hippocampus, and increased Bcl-XL mRNA level in the cortex and hippocampus of 6-day-old-rat pups 24 h after injection. Administration of clonidine 20 min after yohimbine administration abolished its effect on Bcl-XL mRNA level in the hippocampus.