Publications by authors named "F A Hamid"

In the realm of genetic information, fusion transcripts contribute to the intricate complexity of the transcriptome across various organisms. Recently, Cong et al. investigated these RNAs in rice, maize, soybean, and arabidopsis (Arabidopsis thaliana), revealing conserved characteristics.

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Commercial battery separators are made of polyolefin polymers due to their desired mechanical strength and chemical stability. However, these materials are not biodegradable and are challenging to recycle. Considering the environmental issues from polyolefins, biodegradable polymers can be developed as separators to reduce the potential waste from polyolefin separators.

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The expression of eukaryotic genes relies on the precise 3'-terminal cleavage and polyadenylation of newly synthesized pre-mRNA transcripts. Defects in these processes have been associated with various diseases, including cancer. While cancer-focused sequencing studies have identified numerous driver mutations in protein-coding sequences, noncoding drivers - particularly those affecting the cis-elements required for pre-mRNA cleavage and polyadenylation - have received less attention.

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Article Synopsis
  • The study identifies 169,197 fusion transcripts in various plant species, suggesting that these transcripts contribute to physiological processes beyond cancer, including stress responses and morphological traits.
  • By analyzing various datasets, the researchers confirm the active translation of some fusion transcripts and explore how DNA sequence organization and chromatin structure influence their formation.
  • The findings indicate that a large number of fusion events result from alternative splicing and that genes located near each other are more likely to fuse, with many fusion transcripts not being translated into proteins.
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Background: Endophthalmitis is a severe inflammation of the internal ocular structures, usually caused by bacterial or fungal infections, and can lead to rapid, irreversible blindness. Fungal endophthalmitis (FE), primarily due to Candida albicans and Aspergillus, is less common than bacterial endophthalmitis but has shown an increase in prevalence over the past two decades. Diagnosing FE is challenging and often delayed due to the time-consuming nature of traditional culture methods.

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