Disclosing long-term tolerance, efficacy and penetration properties of hyaluronic acid-coated latanoprost-loaded liposomes as chronic glaucoma therapy.

Frequent topical administration of hypotensive eye drops in glaucoma patients may lead to the development of dry eye disease (DED) symptoms, because of tear film destabilization and the adverse effects associated with antiglaucoma formulations. To address all this, in the current study preservative-free latanoprost-loaded (0.005 % w/v) synthetic phosphatidylcholine (1,2-dioleoyl-sn-glycero-3-phosphocholine 0.

The Effects of Post-Warm-Up Active and Passive Rest Periods on a Vigilance Task in Karate Athletes.

This study aimed to analyze how active versus passive rest periods after a warm-up influence performance in psychomotor vigilance tasks (PVT). Twenty amateur karate athletes participated in a randomized cross-over study consisting of two sessions with either a 20 min active rest involving kata techniques or passive rest. PVT was administered before and after these conditions to assess the changes in reaction time.

Relationships between physical fitness and match running demands during a futsal congested-weeks training camp.

This study examines the relationships between body composition, anthropometry and physical fitness measures, and internal and external load (match physical and running demands) during a congested period of an overseas futsal training camp. Eleven under-20 national futsal players participated in a eleven-day training camp. During the matches, exercise heart rate (HR) and locomotion profiles were recorded via a Polar Team Pro system as the players' internal and external load.

The First Steps of the Visual Cycle in Human Rod and Cone Photoreceptors.

Purpose: Light detection destroys the visual pigment. Its regeneration, necessary for the recovery of light sensitivity, is accomplished through the visual cycle. Release of all-trans retinal by the light-activated visual pigment and its reduction to all-trans retinol comprise the first steps of the visual cycle.