Risk Assessment of Mercury in Soil, Water, and Sediments Collected in a Region Impacted by Gold Mining.

This work reports the determination of mercury and the assessment of health risks in water, river sediments, and soil samples collected in the city of , Brazil, located in a region impacted by gold mining. The mercury determinations were performed using the direct method analyzer (DMA) method, which was carefully validated according to the IUPAC recommendations. Total mercury contents ranged from 0.

Allergy to ustekinumab: Validating skin tests for diagnostic and therapeutic decision-making.

Monoclonal antibodies have gained prominence in treating cancer and inflammatory diseases, but their increased use is linked to rising hypersensitivity reactions. Our case report focuses on a 32-year-old female with Crohn's disease treated initially with adalimumab and later with ustekinumab. Despite ustekinumab's generally safe profile, the patient developed increasingly severe mucocutaneous reactions.

Effective desensitization in an IgE-mediated hypersensitivity reaction to tocilizumab in neuromyelitis optica.

Neuromyelitis optica is a rare, inflammatory autoimmune disease of the central nervous system. Tocilizumab is a humanized monoclonal antibody, which targets the inhibition of the interleukin-6 receptor, a mediator with an important role in the pathophysiological mechanism of neuromyelitis optica. Hypersensitivity reactions to tocilizumab are rare, but similar to other biological drugs can elicit a hypersensitivity reaction.

Mechanical Performance Enhancement in Natural Fibre-Reinforced Thermoplastic Composites Through Surface Treatment and Matrix Functionalisation.

This study aims to investigate the behaviour of thermoplastic composites reinforced with natural fibres. Composite materials were developed using reactive methyl methacrylate (MMA) resin, commercially known as Elium (Arkema, Colombes, France), with the incorporation of cellulose nanocrystals (CNCs), dispersed in the matrix at different concentrations. Natural fibres, such as flax, were chemically treated by immersion in an aqueous solution based on NaHCO, during different periods of exposure.

Primary Health Care in context with the plurality in the care of people with tuberculosis.

Objective: to analyze the plurality of care provided to individuals with tuberculosis in Primary Health Care services in Rio de Janeiro, RJ, Brazil.

Method: this qualitative study was conducted from 2017 to 2021. Discourse Analysis was adopted as the theoretical-methodological framework.