Publications by authors named "F A Farley"

Background: Elevated serum titanium levels have been found in patients with early onset scoliosis (EOS) treated with traditional growing rods (TGR), magnetically controlled growing rods (MCGR), and vertical expandable prosthetic titanium rib (VEPTR). No studies have investigated whether serum titanium remains persistently elevated and if titanium is excreted. Our purpose was to compare serum titanium levels in patients with EOS with growth-friendly instrumentation to age-matched controls and evaluate urine titanium and serial serum titanium levels in patients with EOS.

View Article and Find Full Text PDF

Ste5 is a prototype of scaffold proteins that regulate activation of mitogen-activated protein kinase (MAPK) cascades in all eukaryotes. Ste5 associates with many proteins including Gβγ (Ste4), Ste11 MAPKKK, Ste7 MAPKK, Fus3 and Kss1 MAPKs, Bem1, Cdc24. Here we show that Ste5 also associates with heat shock protein 70 chaperone (Hsp70) Ssa1 and that Ssa1 and its ortholog Ssa2 are together important for Ste5 function and efficient mating responses.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluated the effectiveness of surgical vs. non-surgical treatments for midshaft clavicle fractures in adolescents over a five-year period, involving 416 patients with a focus on those aged 10 to 18.
  • Both groups had comparable outcomes in terms of patient-reported outcomes (PROs) after two years, suggesting similar effectiveness between surgical and non-surgical options.
  • The findings revealed no significant differences in recovery scores, despite surgical patients being older and having more severe fractures, ultimately challenging the initial hypothesis that surgery would lead to better results.
View Article and Find Full Text PDF

An abnormal or absent superficial abdominal reflex (SAR) may be associated with an underlying spinal cord syrinx. The sensitivity of an abnormal or absent SAR and the relationship to Chiari malformation type I (CM-I) or syrinx morphology has not been studied. We aimed to describe the relationship between SAR abnormalities and syrinx size, location, and etiology.

View Article and Find Full Text PDF

Memorializes James (Jim) R. Flynn (1934-2020). Jim was one of psychology's most influential thinkers even though he was not a psychologist, receiving a PhD in 1958 in politics and moral philosophy at the University of Chicago.

View Article and Find Full Text PDF