Conventional MRI-Based Structural Disconnection and Morphometric Similarity Networks and Their Clinical Correlates in Multiple Sclerosis.

Background And Objectives: Although multiple sclerosis (MS) can be conceptualized as a network disorder, brain network analyses typically require advanced MRI sequences not commonly acquired in clinical practice. Using conventional MRI, we assessed cross-sectional and longitudinal structural disconnection and morphometric similarity networks in people with MS (pwMS), along with their relationship with clinical disability.

Methods: In this longitudinal monocentric study, 3T structural MRI of pwMS and healthy controls (HC) was retrospectively analyzed.

Ultrasensitive detection and quantification of bovine Deltapapillomavirus in the semen of healthy horses.

BPV1, BPV2, BPV13, and BPV14 are all genotypes of bovine delta papillomaviruses (δPV), of which the first three cause infections in horses and are associated with equine sarcoids. However, BPV14 infection has never been reported in equine species. In this study, we examined 58 fresh and thawed commercial semen samples from healthy stallions.

A multi-residue method based on solid phase extraction followed by HPLC-HRMS/MS analysis for the determination of dyes and additives released from polyester fibres after degradation.

Microfibres released from textiles are one of the most common types of microplastics (MPs) found in the environment. Whether they are synthetic or natural, they can undergo degradation in different environmental matrices. This may result in the leaching of a variety of chemicals, mainly textile dyes and additives of high toxicity that need to be regulated.

Normative values of the brief international cognitive assessment for multiple sclerosis (BICAMS) in an Italian young adolescent population: the influence of age, sex, and education.

Background: The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) is the most widely used in clinical practice and the least time-consuming battery to estimate cognitive function in adults with Multiple Sclerosis (MS), while it has been included in few studies on young MS, also because of the absence of normative values.

Objective: The aim of this study is to evaluate the impact of age, sex and education on BICAMS scores in a young adolescent population.

Methods: We administered the BICAMS to 169, 11-to-18-year-old, healthy subjects.

Are Biobased Microfibers Less Harmful than Conventional Plastic Microfibers: Evidence from Earthworms.

Biobased plastics are sometimes promoted as "environmentally friendly" compared to their conventional petrochemical-based counterparts, but their ecotoxicity is only partially understood. Biobased fibers are widely used in clothing and wet wipes and can accumulate in soils through the application of biosolid fertilizers. This study examined the lethal thresholds and sublethal toxicity of chemically characterized, additive-free, biobased (viscose and lyocell) compared to petrochemical-based (polyester) fibers on the key ecosystem engineer, .