A clinical trial of phenoxymethyl penicillin for adjunctive treatment of juvenile periodontitis.

A double-blind clinical trial of oral penicillin as an adjunct to conventional treatment of localized juvenile periodontitis (JP) was conducted. Sixteen subjects with JP were paired on the basis of general similarity of disease, and within each pair the persons were assigned randomly, one to a placebo group and one to a penicillin group. Neither patients nor therapist/examiner were aware of whether placebo or penicillin was being taken.

Localized juvenile periodontitis and generalized severe periodontitis: clinical findings.

Medically healthy subjects (N = 103), 10-32 years of age, with localized (juvenile periodontitis = JP) or generalized (severe periodontitis = SP) advanced periodontal disease were analyzed for interrelationships of sex, race, age and clinical findings. Females predominated (2:1) in both JP and SP. There were significantly more subjects of the black race in JP, but when age was included as a cofactor the race distinction became insignificant.