A Novel multi-fruit acids formula design on molecular basis for skin brightening via a system biology approach.

Background: Fruit acids have long been recognized as highly effective actives with world-wide popularity, covering skin peeling, anti-acne, anti-wrinkle applications, and skin depigmentation.

Aims: There are complicated interconnections between the fruit acid formula and skin pigmentation behaviors. However, the lack of systematic researches on multi-ingredient formula restricted our understanding on its mechanism.

Analysis of a FANCE Splice Isoform in Regard to DNA Repair.

The FANC-BRCA DNA repair pathway is activated in response to interstrand crosslinks formed in DNA. A homozygous mutation in 1 of the 17 Fanconi anemia (FA) genes results in malfunctions of this pathway and development of FA syndrome. The integrity of this protein network is essential for good maintenance of DNA repair process and genome stability.

Biosonar signals impinging on the target during interception by big brown bats, Eptesicus fuscus.

Big brown bats (Eptesicus fuscus) were videotaped in the dark with a night-vision lens and infrared illumination while flying repeatedly along the same straight course to seize a tethered mealworm or a small electret microphone used to record biosonar signals impinging on the target. Bats emitted frequency-modulated sounds with first to third harmonics covering frequencies from 23 to 105 kHz. As the bats neared the target, the first harmonic shifted lower in frequency while the third harmonic strengthened and the fourth harmonic, and sometimes the fifth harmonic, appeared.

Passive standoff detection of SF6 at a distance of 5.7 km by differential Fourier transform infrared radiometry.

Recent results are presented on the passive detection, identification, and quantification of a vapor cloud of SF6 measured at a horizontal standoff distance of 5.7 km using a dual-beam interferometer optimized for background signal suppression. The measurements were performed at Defense Research and Development Canada (DRDC)-Valcartier during a number of recent open-air experiments.

Passive remote monitoring of chemical vapors by differential Fourier-transform infrared radiometry: results at a range of 1.5 km.

A method for the passive remote monitoring of chemical vapors by differential Fourier-transform infrared radiometry is presented to determine the characteristics of a chemical vapor plume from a stack located at a distance of more than 1 km from the sensor. This measurement technique is based on the use of a double-beam Fourier-transform infrared spectrometer that is optimized for optical subtraction. A description of the interferometer (compact atmospheric sounding interferometer) is given along with the algorithm (GASEM) that has been developed for the on-line detection, identification, and quantification of chemical vapor plumes.