Artificial compressibility method for strongly anisothermal low Mach number flows.

Artificial compressibility methods aim to reduce the stiffness of the compressible Navier-Stokes equations by artificially decreasing the velocity of acoustic waves in the fluid. This approach has originally been developed as an alternative to the incompressible Navier-Stokes equations as this avoids the resolution of a Poisson equation. This paper extends the method to anisothermal low Mach number flows, allowing the simulations of subsonic flows submitted to large temperature variations, including dilatational effects.

Ozone-Induced Aryl Hydrocarbon Receptor Activation Controls Lung Inflammation via Interleukin-22 Modulation.

Airborne ozone exposure causes severe lung injury and inflammation. The aryl hydrocarbon Receptor (AhR) (1), activated in pollutant-induced inflammation, is critical for cytokine production, especially IL-22 and IL-17A. The role of AhR in ozone-induced lung inflammation is unknown.

Four-And-A-Half LIM-Domain Protein 2 (FHL2) Deficiency Aggravates Cholestatic Liver Injury.

Cholestasis occurs in different clinical circumstances and leads to severe hepatic disorders. The four-and-a-half LIM-domain protein 2 (FHL2) is a scaffolding protein that modulates multiple signal transduction pathways in a tissue- and cell context-specific manner. In this study, we aimed to gain insight into the function of FHL2 in cholestatic liver injury.

[Dr. Stéphane Leduc and the first treatments of cancer by irradiation in Nantes and France].

In August 1883, a Chair of physics was created in Nantes with Dr. Leduc (1853-1939) as the first teacher. Physician and biophysicist, he was a pioneer and visionary in many areas, including the "synthetic biology".