Antioxidant and Antibacterial Screening and Hg(II) Sensing, Activities of Cu(II)pyridine-2,6-dicarboxylate Complexes.

In this study five different complexes of Cu(II) were synthesized for the purpose of environmentally notorious mercury sensing and preliminary biological screening. Pyridine-2,6-dicarboxylic acid (also known as dipicolinic acid, and abbreviated as HDPA), 3-phenyl pyrazole (3-ppz), 4-iodo-1H-pyrazole (4-ipz), 4-nitropyrazole (4-npz), 4-bromopyrazole (4-bpz), and 4-chloropyrazole (4-cpz) were chosen as potential ligands. The synthesized complexes labelled as 1-5, namely [Cu(DPA)(3-ppz)], [Cu(DPA)(4-ipz)], [Cu(DPA)(4-npz)], [Cu(DPA)(4-bpz)], [Cu(DPA)(4-cpz)], were proposed based on spectroscopic data (FTIR, TGA, and UV-visible spectroscopy).

Antioxidant, antibacterial, enzyme inhibition and fluorescence characteristics of unsymmetrical thiourea derivatives.

A series of six unsymmetrical thiourea derivatives, namely 1-cyclohexyl-3-(pyridin-2-yl) thiourea (), 1-cyclohexyl-3-(3-methylpyridin-2-yl)thiourea (), 1-cyclohexyl-3-(2,4-dimethylphenyl) thiourea (), 1-(4-chlorophenyl)-3-cyclohexylthiourea (), 1-(3-methylpyridin-2-yl)-3-phenylthiourea (), and 1-(3-chlorophenyl)-3-phenylthiourea (), were successfully synthesized via reaction between different amines with isothiocyanates under a non-catalytic environment. Structural elucidation of compounds () was performed using FT-IR and NMR (H and C) spectroscopy. The infrared spectra displayed characteristic stretching vibrations, while the C NMR chemical shifts of the thiourea moiety (C[bond, double bond]S) were observed in the range of 179.

Phytoremediation of formaldehyde by three selected non-native indoor plant species.

Formaldehyde is an organic volatile compound and a commonly used chemical in various construction materials thus causing dwellers to be exposed to it inside a building. Its remediation from indoor air has been carried out through various techniques where potted plants and living walls are at the front foot. It is necessary to study plants under various conditions for their efficiency.

Predicting medical waste generation and associated factors using machine learning in the Kingdom of Bahrain.

Effective planning and managing medical waste necessitate a crucial focus on both the public and private healthcare sectors. This study uses machine learning techniques to estimate medical waste generation and identify associated factors in a representative private and a governmental hospital in Bahrain. Monthly data spanning from 2018 to 2022 for the private hospital and from 2019 to February 2023 for the governmental hospital was utilized.

Metal-Organic Frameworks (MOFs)-Based Sensors for the Detection of Heavy Metals: A Review.

Metal-organic-frameworks (MOFs) have emerged as promising candidates in different scientific disciplines owing to their intriguing characteristics. Their unique structural properties, including large surface area to volume ratio with multi-functionalities and ultra-high porosity, tunability, uniformity, and easy derivation and fabrication, render them effective materials for sensing applications. The detection of heavy metals in different environmental matrices using various MOF-based sensors is in practice.

Organic Molecules Containing N, S and O Heteroatoms as Sensors for the Detection of Hg(II) Ion; Coordination and Efficiency toward Detection.

Rapid detection of potentially toxic heavy metals like Hg(II) has attracted great attention in the last few decades due to the importance to maintain a safe and sustainable environment for human beings. Coordination chemistry and concepts therein, play an important role in the detection of Hg(II). Size, charge, and nature of the donor atom and the respective cation (metal ion), are crucial in selective interactions between the sensor and metal ions.

Phytoremediation of indoor formaldehyde by plants and plant material.

Formaldehyde evolves from various household items and is of environmental and public health concern. Removal of this contaminant from the indoor air is of utmost importance and currently, various practices are in the field. Among these practices, indoor plants are of particular importance because they help in controlling indoor temperature, moisture, and oxygen concentration.

Levofloxacin Cocrystal/Salt with Phthalimide and Caffeic Acid as Promising Solid-State Approach to Improve Antimicrobial Efficiency.

To overcome the issue of multidrug resistant (MDR) microbes, the exploration of ways to improve the antimicrobial efficiency of existing antibiotics is one of the promising approaches. In search of synthons with higher efficiency, in current investigations, cocrystal and amorphous salt of levofloxacin hemihydrate (LEV) were developed with phthalimide (PTH) and caffeic acid (CFA). New materials were characterized with the help of FT-IR, Raman spectroscopy, powder X-ray diffraction (PXRD), differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA).

Enhancing Dissolution Rate and Antibacterial Efficiency of Azithromycin through Drug-Drug Cocrystals with Paracetamol.

Cocrystallization is a promising approach to alter physicochemical properties of active pharmaceutical ingredients (hereafter abbreviated as APIs) bearing poor profile. Nowadays pharmaceutical industries are focused on preparing drug-drug cocrystals of APIs that are often prescribed in combination therapies by physicians. Physicians normally prescribe antibiotic with an analgesic/antipyretic drug to combat several ailments in a better and more efficient way.

Estimation of COVID-19 generated medical waste in the Kingdom of Bahrain.

Coronavirus disease 2019 (COVID-19) is not only a great matter of concern from a medical and health perspective, but it is a serious threat to the environment in terms of waste generated during the prevention and cure of COVID-19. The world has so far compromised more than 3 million human lives, and millions are being infected. Environmental threat is most serious because it can cause secondary complications.

Thiourea Derivatives, Simple in Structure but Efficient Enzyme Inhibitors and Mercury Sensors.

In this study six unsymmetrical thiourea derivatives, 1-isobutyl-3-cyclohexylthiourea (), 1-butyl-3-cyclohexylthiourea (), 1-(3-chlorophenyl)-3-cyclohexylthiourea (), 1-(1,1-dibutyl)-3-phenylthiourea (), 1-(2-chlorophenyl)-3-phenylthiourea () and 1-(4-chlorophenyl)-3-phenylthiourea () were obtained in the laboratory under aerobic conditions. Compounds and are crystalline and their structure was determined for their single crystal. Compounds is monoclinic system with space group P2/n while compound is trigonal, space group .

A scaffolded approach to unearth potential antibacterial components from epicarp of Malaysian Nephelium lappaceum L.

The emergence and spread of antimicrobial resistance have been of serious concern to human health and the management of bacterial infectious diseases. Effective treatment of these diseases requires the development of novel therapeutics, preferably free of side effects. In this regard, natural products are frequently conceived to be potential alternative sources for novel antibacterial compounds.

Medicinal Importance, Coordination Chemistry with Selected Metals (Cu, Ag, Au) and Chemosensing of Thiourea Derivatives. A Review.

Thiourea and its derivatives are versatile compounds used in several fields of life ranging from medicinal to chemosensor applications. In this review article, generally used preparative methods of thiourea, its coordination compounds with selected metals (Cu, Ag, Au) for biological and medicinal applications and the potentials of thiourea derivatives in analytical chemistry as chemosensors have been discussed. The improved activities of these derivatives in the field of pharmaceutical chemistry can be achieved by coordination with a suitable metal ion.

Bioaccumulation of Cr, Ni, Cd and Pb in the Economically Important Freshwater Fish Schizothorax plagiostomus from Three Rivers of Malakand Division, Pakistan: Risk Assessment for Human Health.

Contamination of freshwater ecosystems such as rivers with hazardous heavy metals is an environmental problem of public health concern. Accumulation of potentially toxic heavy metals in freshwater fish causes a potential health threat to their consumers including humans. The present research aimed to (1) investigate the accumulation of four potentially toxic heavy metals viz.

Isolation, crystal structure determination and cholinesterase inhibitory potential of isotalatizidine hydrate from Delphinium denudatum.

Context: Delphinium denudatum Wall (Ranunculaceae) is a rich source of diterpenoid alkaloids and is widely used for the treatment of various neurological disorders such as epilepsy, sciatica and Alzheimer's disease.

Objective: The present study describes crystal structure determination and cholinesterase inhibitory potential of isotalatazidine hydrate isolated from the aerial part of Delphinium denudatum.

Materials And Methods: Phytochemical investigation of Delphinium denudatum resulted in the isolation of isotalatazidine hydrate in crystalline form.

Chemical and biological evaluation of Ranunculus muricatus.

Ranunculus muricatus is commonly known as spiny fruit buttercup and is used in the treatment of intermittent fevers, gout and asthma. Qualitative analysis of phytochemicals of Ranunculus muricatus indicated the presence of saponins, tannins, phenols, flavonoids and alkaloids. Saponins were present in high amount as compared with other chemicals.

Phytoremediation of heavy metals--concepts and applications.

The mobilization of heavy metals by man through extraction from ores and processing for different applications has led to the release of these elements into the environment. Since heavy metals are nonbiodegradable, they accumulate in the environment and subsequently contaminate the food chain. This contamination poses a risk to environmental and human health.