Comparative analysis of effects induced by hyaluronic acid and its combined formula on skin functional parameters in second-degree photoaging.

Background And Aims: The study aimed to compare the effectiveness of intradermal injections of modified hyaluronic acid (mHA) and combined injections of platelet-rich plasma (PRP) and mHA (HA-PRP) on clinical and functional parameters in women with second-degree photoaging.

Methods: Seventy-six healthy female participants diagnosed with second degree of skin photoaging were involved in two interventional study groups. The first group was treated with "bio-reparative" method (mHA) and the second group with "combined HA-PRP therapy".

Ichthyosiform mycosis fungoides.

Malignancy-associated acquired ichthyosis is well known, but the ichthyosiform subset of mycosis fungoides (MF) is rarely reported. We report on two patients with a clinical presentation for whom diagnosis of mycosis fungoides was established on histological grounds. In both cases, long term remission was obtained with non aggressive therapies.